A rare case of conjunctival malignant melanoma with orbital invasion

被引:2
作者
Rajbhandari, Yogita [1 ]
Gupta, Sharad [2 ]
Yadav, Reena [2 ]
Manandhar, Ashma [3 ]
Mon, Aye Myat [1 ]
Joshi, Pramiti [1 ]
Shrestha, Gulshan Bahadur [4 ]
机构
[1] Tilganga Inst Ophthalomol, Kathmandu, Nepal
[2] Sagarmatha Choudhary Eye Hosp, Siraha, Lahan, Nepal
[3] Biratnagar Eye Hosp, Biratnagar, Nepal
[4] BP Koirala Lions Ctr Ophthalm Studies, Maharajgunj Kathmandu, Nepal
关键词
Conjunctival malignant melanoma; De novo; Incisional biopsy; OCULAR MELANOMA;
D O I
10.3126/nepjoph.v11i1.25425
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Background: Conjunctival malignant melanoma is a rare ocular malignancy most commonly affecting mostly the elderly population. It is a pigmented lesion which can arise from primary acquired melanosis, de novo or from preexisting nevus. Case: A 63 year old male presented with a chief complaints rapidly increasing mass in the left eye for two months following trauma with a wooden stick. He had preexisting nevus in the same eye. His best corrected visual acuity was 6/12 in right eye and 1/60 left eye respectively. Slit lamp biomicroscopy examination showed 4 cm x 4 cm pigmented mass in the nasal bulbar and inferior palpebral conjunctiva causing mechanical ectropion of the lower lid with keratinization of palpebral conjunctiva. Incisional biopsy of conjunctiva showed malignant melanoma. On computed tomography, there was expansion of bony orbit. Considering all the findings, exenteration of the left orbit was done. Histopathological report of exenterated mass was suggestive of malignant melanoma of conjunctiva. Conclusion: Conjunctival melanoma is a rare malignant tumor of eye which has high metastasis rate and the treatment option is surgery with adjuvant therapy.
引用
收藏
页码:77 / 81
页数:5
相关论文
共 11 条
  • [1] Prognostic value of clinical and histopathological parameters in conjunctival melanomas: a retrospective study
    Anastassiou, G
    Heiligenhaus, A
    Bechrakis, N
    Bader, E
    Bornfeld, N
    Steuhl, KP
    [J]. BRITISH JOURNAL OF OPHTHALMOLOGY, 2002, 86 (02) : 163 - 167
  • [2] Brownstein Seymour, 2004, Cancer Control, V11, P310
  • [3] Jovanovic P, 2013, INT J CLIN EXP PATHO, V6, P1230
  • [4] ORBITAL EXENTERATION IN 95 CASES OF PRIMARY CONJUNCTIVAL MALIGNANT-MELANOMA
    PARIDAENS, ADA
    MCCARTNEY, ACE
    MINASSIAN, DC
    HUNGERFORD, JL
    [J]. BRITISH JOURNAL OF OPHTHALMOLOGY, 1994, 78 (07) : 520 - 528
  • [5] Salazar Mendez R, 2012, ARCH SOCESPOFTALMOL, V89, P82
  • [6] MELANOMAS OF EYE AND OTHER NON-CUTANEOUS SITES - EPIDEMIOLOGIC ASPECTS
    SCOTTO, J
    FRAUMENI, JF
    LEE, JAH
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1976, 56 (03) : 489 - 491
  • [7] Conjunctival melanoma
    Seregard, S
    [J]. SURVEY OF OPHTHALMOLOGY, 1998, 42 (04) : 321 - 350
  • [8] Shields C L, 2000, Trans Am Ophthalmol Soc, V98, P471
  • [9] Ocular melanoma: relatively rare but requiring respect
    Shields, Carol L.
    Shields, Jerry A.
    [J]. CLINICS IN DERMATOLOGY, 2009, 27 (01) : 122 - 133
  • [10] Shields CL, 2011, OPHTHALMOLOGY, V118