Prognostic aspects of dynamic contrast-enhanced magnetic resonance imaging in synchronous distant metastatic rectal cancer

被引：29

作者：

Yu, Jing ^{[1
]}

Xu, Qing ^{[1
]}

Huang, Dong-Ya ^{[2
]}

Song, Jia-Cheng ^{[1
]}

Li, Yan ^{[1
]}

Xu, Lu-Lu ^{[1
]}

Shi, Hai-Bin ^{[1
]}

机构：

[1] Nanjing Med Univ, Affiliated Hosp 1, Dept Radiol, 300 Guangzhou Rd, Nanjing 210029, Jiangsu, Peoples R China

[2] Nanjing Med Univ, Dept Gen Surg, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R China

来源：

EUROPEAN RADIOLOGY | 2017年 / 27卷 / 05期

关键词：

DCE-MRI; Rectal cancer; Synchronous distant metastasis; Quantitative parameters; Clinicopathological factors; EXTRAMURAL VASCULAR INVASION; COLORECTAL-CANCER; LYMPHOVASCULAR INVASION; PERFUSION PARAMETERS; CURATIVE SURGERY; E-CADHERIN; MRI; ANGIOGENESIS; MODEL;

D O I：

10.1007/s00330-016-4532-y

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

To explore the correlations between DCE-MRI quantitative parameters and synchronous distant metastasis and the clinicopathological factors in rectal cancers. Sixty-three patients with rectal cancer (synchronous distant metastasis, n = 31; non-metastasis, n = 32) were enrolled in this study. Student's t test and ANOVA were used to compare DCE-MRI parameters (K (trans) , K (ep) and V (e) ). The receiver operating characteristic (ROC) analysis was used to find the reasonable threshold of DCE-MRI parameters to differentiate lesions with synchronous distant metastasis from those without metastasis. The K (trans) , K (ep) , and V (e) value were significantly higher in the lesions with distant metastasis than in the lesions without distant metastasis (0.536 +/- 0.242 vs. 0.299 +/- 0.118 min(-1), p < 0.001; 1.598 +/- 0.477 vs. 1.341 +/- 0.390 min(-1), p = 0.022; and 0.324 +/- 0.173 vs. 0.249 +/- 0.091, p = 0.034; respectively). The K (trans) showed the highest AUCs of 0.788 (p < 0.001), with sensitivity of 61.29 % and specificity of 87.5 %, respectively. DCE-MRI parameters may represent a prognostic indicator for synchronous distant metastases in patients with rectal cancer. aEuro cent The K (trans) , K (ep) and V (e) values correlated with synchronous distant metastasis. aEuro cent Higher K (trans) , K (ep) and V (e) values were noted among patients with metastasis. aEuro cent DCE-MRI parameters might represent a prognostic indicator for synchronous distant metastases.

引用

页码：1840 / 1847

页数：8

共 33 条

[1] Discriminant analysis to classify glioma grading using dynamic contrast-enhanced MRI and immunohistochemical markers [J].