Pregnancy recognition and abnormal offspring syndrome in cattle

被引:42
作者
Farin, C. E. [1 ]
Farmer, W. T. [1 ]
Farin, P. W. [2 ]
机构
[1] N Carolina State Univ, Dept Anim Sci, Raleigh, NC 27965 USA
[2] N Carolina State Univ, Dept Populat Hlth & Pathobiol, Raleigh, NC 27695 USA
关键词
AIRN; embryo; fetus; in vitro production; insulin-like growth factor receptor 2; GROWTH-FACTOR-I; INTERFERON-TAU GENE; OVINE TROPHOBLAST PROTEIN-1; MESSENGER-RNA EXPRESSION; VITRO-PRODUCED EMBRYOS; PREIMPLANTATION BOVINE EMBRYOS; INDUCED TRANSCRIPTOME CHANGES; ORGANIC CATION TRANSPORTERS; CYTOSINE METHYLATION LEVELS; CROSS-REACTIVE PROTEIN;
D O I
10.1071/RD09217
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Development of the post-hatching conceptus in ruminants involves a period of morphological expansion that is driven by complex interactions between the conceptus and its intrauterine environment. As a result of these interactions, endometrial physiology is altered, leading to establishment of the pregnancy and continued development of the placenta. Disruption of normal fetal and placental development can occur when embryos are exposed to manipulations in vitro or when inappropriate endocrine sequencing occurs in vivo during the pre- and peri-implantation periods. The present review addresses the development of the post-hatching bovine conceptus, its interactions with the maternal system and changes in development that can occur as a result of in vivo and in vitro manipulations of the bovine embryo.
引用
收藏
页码:75 / 87
页数:13
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