Segmental Darier disease

被引:0
作者
Schmitt, L. [1 ]
Roos, S. [1 ]
Raulin, C. [1 ,2 ]
Karsai, S. [1 ]
机构
[1] Laserklin Karlsruhe, D-76133 Karlsruhe, Germany
[2] Univ Hautklin, Heidelberg, Germany
来源
HAUTARZT | 2009年 / 60卷 / 12期
关键词
Pulsed Dye-Laser; Laser; Darier disease; Keratosis Follicularis; PULSED-DYE-LASER; HAILEY-HAILEY-DISEASE; KERATOSIS-FOLLICULARIS; TOPICAL; 5-FLUOROURACIL; LUPUS-ERYTHEMATOSUS; CLINICAL-FEATURES; MANAGEMENT; MUTATIONS; EFFICACY;
D O I
10.1007/s00105-009-1732-2
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Darier disease is often associated with pruritus and an unpleasant odor, causing medical and emotional problems. Ablative laser therapy has proven effective in ameliorating these symptoms. Side effects of this approach include permanent hypopigmentation and a risk of scarring. We present two cases where non-ablative therapy with pulsed dye lasers proved a safe and effective way to manage the intertriginous lesions. Although the mechanism of action is unclear, our success indicates that pulsed dye laser therapy is an option in Darier disease. Larger numbers of patients, ideally in multicenter studies, must be treated in this way to confirm our results.
引用
收藏
页码:995 / 998
页数:4
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