Pyoverdine siderophores: from biogenesis to biosignificance

被引:399
作者
Visca, Paolo
Imperi, Francesco
Lamont, Iain L. [1 ]
机构
[1] Univ Rome Tre, Dept Biol, I-00146 Rome, Italy
[2] Natl Inst Infect Dis L Spallanzani, Mol Microbiol Unit, I-00149 Rome, Italy
[3] Univ Otago, Dept Biochem, Dunedin 9054, New Zealand
关键词
D O I
10.1016/j.tim.2006.11.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pyoverdines are a group of structurally related siderophores produced by fluorescent Pseudomonas species. Recent genomic and biochemical data have shed new light on the complex molecular steps of pyoverdine biogenesis and explained the chemical diversity of these compounds. In the opportunistic pathogen Pseudomonas aeruginosa, pyoverdine is necessary for infection in several different disease models. The occurrence of pyoverdine-defective strains in chronic infections of patients with cystic fibrosis and the extremely high sequence diversity of genes involved in pyoverdine synthesis and uptake indicate that pyoverdine production is subject to high evolutionary pressure. Pyoverdine-dependent iron transport is also crucial for biofilm development, further expanding the importance of these siderophores in Pseudomonas biology.
引用
收藏
页码:22 / 30
页数:9
相关论文
共 86 条
[11]   Use of plant growth-promoting bacteria for biocontrol of plant diseases:: Principles, mechanisms of action, and future prospects [J].
Compant, S ;
Duffy, B ;
Nowak, J ;
Clément, C ;
Barka, EA .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2005, 71 (09) :4951-4959
[12]   A new regulator linking quorum sensing and iron uptake in Pseudomonas aeruginosa [J].
Cornelis, P ;
Aendekerk, S .
MICROBIOLOGY-SGM, 2004, 150 :752-756
[13]   Diversity of siderophore-mediated iron uptake systems in fluorescent pseudomonads: not only pyoverdines [J].
Cornelis, P ;
Matthijs, S .
ENVIRONMENTAL MICROBIOLOGY, 2002, 4 (12) :787-798
[14]   Study of pyoverdine type and production by Pseudomonas aeruginosa isolated from cystic fibrosis patients:: prevalence of type II pyoverdine isolates and accumulation of pyoverdine-negative mutations [J].
De Vos, D ;
De Chial, M ;
Cochez, C ;
Jansen, S ;
Tümmler, B ;
Meyer, JM ;
Cornelis, P .
ARCHIVES OF MICROBIOLOGY, 2001, 175 (05) :384-388
[15]   Formation of the chromophore of the pyoverdine siderophores by an oxidative cascade [J].
Dorrestein, PC ;
Poole, K ;
Begley, TP .
ORGANIC LETTERS, 2003, 5 (13) :2215-2217
[16]   Acquisition of siderophores in Gram-negative bacteria [J].
Faraldo-Gómez, JD ;
Sansom, MSP .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2003, 4 (02) :105-116
[17]   Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000 [J].
Feil, H ;
Feil, WS ;
Chain, P ;
Larimer, F ;
DiBartolo, G ;
Copeland, A ;
Lykidis, A ;
Trong, S ;
Nolan, M ;
Goltsman, E ;
Thiel, J ;
Malfatti, S ;
Loper, JE ;
Lapidus, A ;
Detter, JC ;
Land, M ;
Richardson, PM ;
Kyrpides, NC ;
Ivanova, N ;
Lindow, SE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (31) :11064-11069
[18]   Biosynthesis of nonribosomal peptides [J].
Finking, R ;
Marahiel, MA .
ANNUAL REVIEW OF MICROBIOLOGY, 2004, 58 :453-488
[19]  
Folschweiller N, 2000, MOL MEMBR BIOL, V17, P123
[20]  
Fuchs Regine, 2001, Current Topics in Medicinal Chemistry, V1, P31, DOI 10.2174/1568026013395542