Clinical grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene: authors' reponse

被引：1
作者：
Guillot-Delost, Maude [2 ,3 ]
Cherai, Mustapha
Hamel, Yamina
Rosenzwajg, Michelle [2 ,3 ]
Baillou, Claude [2 ,3 ]
Simonin, Ghislaine
Leclercq, Virginie
Mariotti-Ferrandiz, Maria Encarnita [2 ,4 ]
Six, Adrien [2 ,4 ,5 ]
Bon-Durand, Veronique
Maury, Sebastien [6 ]
Salomon, Benoit L. [2 ,3 ]
Cohen, Jose L. [2 ,3 ]
Klatzmann, David [2 ,3 ]
Lemoine, Francois M. [1 ,2 ,3 ]
机构：
[1] Grp Hosp Pitie Salpetriere, CNRS, UMR 7211, AP HP,Serv Biotherapies, F-75651 Paris 13, France
[2] Univ Paris 06, Paris, France
[3] CNRS, UMR 7211, Paris, France
[4] CNRS, URA 1961, Paris, France
[5] Inst Pasteur, Dept Immunol, F-75724 Paris, France
[6] Hop Henri Mondor, AP HP, Dept Clin Hematol, F-94010 Creteil, France
来源：
JOURNAL OF GENE MEDICINE | 2009年 / 11卷 / 08期
关键词：
RAPAMYCIN; EXPANSION; CULTURES;
D O I：
10.1002/jgm.1358
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：737 / 738
页数：2
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  • [1] Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance
    Battaglia, M
    Stabilini, A
    Draghici, E
    Gregori, S
    Mocchetti, C
    Bonifacio, E
    Roncarolo, MG
    [J]. DIABETES, 2006, 55 (01) : 40 - 49
  • [2] Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
    Battaglia, Manuela
    Stabilini, Angela
    Migliavacca, Barbara
    Horejs-Hoeck, Jutta
    Kaupper, Thomas
    Roncarolo, Maria-Grazia
    [J]. JOURNAL OF IMMUNOLOGY, 2006, 177 (12) : 8338 - 8347
  • [3] Comment on M. Guillot-Delost et al. (2008;10:834-846): Clinical-grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene
    Battaglia, Manuela
    Strauss, Laura
    Roncarolo, Maria-Grazia
    [J]. JOURNAL OF GENE MEDICINE, 2009, 11 (02) : 180 - 181
  • [4] In vitro-expanded human CD4+CD25+ T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures
    Godfrey, WR
    Ge, YG
    Spoden, DJ
    Levine, BL
    June, CH
    Blazar, BR
    Porter, SB
    [J]. BLOOD, 2004, 104 (02) : 453 - 461
  • [5] Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene
    Guillot-Delost, Maude
    Cherai, Mustapha
    Hamel, Yamina
    Rosenzwajg, Michelle
    Baillou, Claude
    Simonin, Ghislaine
    Leclercq, Virginie
    Mariotti-Ferrandiz, Maria Encarnita
    Six, Adrien
    Bon-Durand, Veronique
    Maury, Sebastien
    Salomon, Benoit L.
    Cohen, Jose L.
    Klatzmann, David
    Lemoine, Francois M.
    [J]. JOURNAL OF GENE MEDICINE, 2008, 10 (08) : 834 - 846
  • [6] Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion
    Hoffmann, Petra
    Eder, Ruediger
    Boeld, Tina J.
    Doser, Kristina
    Piseshka, Biserka
    Andreesen, Reinhard
    Edinger, Matthias
    [J]. BLOOD, 2006, 108 (13) : 4260 - 4267
  • [7] Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells
    Nikolaeva, N
    Bemelman, FJ
    Yong, SL
    van Lier, RAW
    ten Berge, IJM
    [J]. TRANSPLANTATION, 2006, 81 (03) : 445 - 454
  • [8] Functional and phenotypic characteristics of CD4+CD25high Foxp3+ Treg clones obtained from peripheral blood of patients with cancer
    Strauss, Laura
    Bergmann, Christoph
    Whiteside, Theresa L.
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2007, 121 (11) : 2473 - 2483
  • [9] Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin
    Strauss, Laura
    Whiteside, Theresa L.
    Knights, Ashley
    Bergmann, Christoph
    Knuth, Alexander
    Zippelius, Alfred
    [J]. JOURNAL OF IMMUNOLOGY, 2007, 178 (01) : 320 - 329
  • [10] Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells
    Valmori, Danila
    Tosello, Valeria
    Souleimanian, Naira E.
    Godefroy, Emmanuelle
    Scotto, Luigi
    Wang, Yu
    Ayyoub, Maha
    [J]. JOURNAL OF IMMUNOLOGY, 2006, 177 (02) : 944 - 949
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