RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression

被引：21

作者：

Sanclemente, Manuel ^{[1
]}

Nieto, Patricia ^{[1
,4
]}

Garcia-Alonso, Sara ^{[1
]}

Fernandez-Garcia, Fernando ^{[1
]}

Esteban-Burgos, Laura ^{[1
]}

Guerra, Carmen ^{[1
]}

Drosten, Matthias ^{[1
]}

Caleiras, Eduardo ^{[2
]}

Martinez-Torrecuadrada, Jorge ^{[3
]}

Santamaria, David ^{[1
,5
]}

Musteanu, Monica ^{[1
,6
]}

Barbacid, Mariano ^{[1
]}

机构：

[1] Ctr Nacl Invest Oncol, Mol Oncol, Melchor Fernandez Almagro 3, Madrid 28029, Spain

[2] Ctr Nacl Invest Oncol, Biotechnol, Melchor Fernandez Almagro 3, Madrid 28029, Spain

[3] Ctr Nacl Invest Oncol, Struct Biol Programs, Melchor Fernandez Almagro 3, Madrid 28029, Spain

[4] Asociac Espanola Canc AECC, Madrid 28040, Spain

[5] Univ Bordeaux, INSERM, U1218, ACTION Lab,IECB, F-33607 Pessac, France

[6] Univ Complutense Madrid, Dept Biochem & Mol Biol, Fac Pharm, Madrid, Spain

来源：

CANCER CELL | 2021年 / 39卷 / 03期

基金：

欧洲研究理事会;

关键词：

C-RAF; REGRESSION; APOPTOSIS;

D O I：

10.1016/j.ccell.2021.01.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：294 / 296

页数：3

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