Diagnosis for Pheochromocytoma and Paraganglioma: A Joint Position Statement of the Korean Pheochromocytoma and Paraganglioma Task Force

被引：12

作者：

Ku, Eu Jeong ^{[1
]}

Kim, Kyoung Jin ^{[2
,3
]}

Kim, Jung Hee ^{[4
]}

Kim, Mi Kyung ^{[5
]}

Ahn, Chang Ho ^{[6
]}

Lee, Kyung Ae ^{[7
]}

Lee, Seung Hun ^{[8
]}

Lee, You-Bin ^{[9
]}

Park, Kyeong Hye ^{[10
]}

Choi, Yun Mi ^{[11
]}

Hong, Namki ^{[2
]}

Hong, A. Ram ^{[12
]}

Kang, Sang-Wook ^{[13
]}

Park, Byung Kwan ^{[14
]}

Seong, Moon-Woo ^{[15
]}

Kim, Myungshin ^{[16
]}

Jung, Kyeong Cheon ^{[17
]}

Jung, Chan Kwon ^{[18
]}

Cho, Young Seok ^{[19
]}

Paeng, Jin Chul ^{[20
]}

Kim, Jae Hyeon ^{[9
]}

Ryu, Ohk-Hyun ^{[21
]}

Rhee, Yumie ^{[2
]}

Kim, Chong Hwa ^{[22
]}

Lee, Eun Jig ^{[2
]}

机构：

[1] Chungbuk Natl Univ, Chungbuk Natl Univ Hosp, Dept Internal Med, Coll Med, Cheongju, South Korea

[2] Yonsei Univ, Coll Med, Dept Internal Med, Severance Hosp,Endocrine Res Inst, 50-1 Yonsei Ro, Seoul 03722, South Korea

[3] Korea Univ, Dept Internal Med, Coll Med, Seoul, South Korea

[4] Seoul Natl Univ, Div Endocrinol & Metab, Dept Med, Seoul Natl Univ Hosp,Coll Med, Seoul, South Korea

[5] Kennyung Univ, Dept Internal Med, Sch Med, Daegu, South Korea

[6] Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea

[7] Jeonbuk Natl Univ, Div Endocrinol & Metab, Dept Internal Med, Med Sch, Jeonju, South Korea

[8] Univ Ulsan, Asan Med Ctr, Coll Med, Div Endocrinol & Metab,Dept Med, Ulsan, South Korea

[9] Sungkyunkwan Univ, Dept Med, Div Endocrinol & Metab, Samsung Med Ctr,Sch Med, Seoul, South Korea

[10] Natl Hlth Insurance Serv, Div Endocrinol & Metab, Ilsan Hosp, Dept Internal Med, Goyang, South Korea

[11] Hallym Univ, Dongtan Sacred Heart Hosp, Dept Internal Med, Coll Med, Hwaseong, South Korea

[12] Chonnam Natl Univ, Dept Internal Med, Med Sch, Gwangju, South Korea

[13] Yonsei Univ, Thyroid Endocrine Surg Div, Dept Surg, Coll Med, Seoul, South Korea

[14] Sungkyunkwan Univ, Samsung Med Ctr, Dept Radiol, Sch Med, Seoul, South Korea

[15] Seoul Natl Univ, Coll Med, Dept Lab Med, Seoul Natl Univ Hosp, Seoul, South Korea

[16] Catholic Univ Korea, Coll Med, Dept Lab Med, Seoul, South Korea

[17] Seoul Natl Univ, Dept Pathol, Coll Med, Seoul, South Korea

[18] Catholic Univ Korea, Dept Hosp Pathol, Coll Med, Seoul, South Korea

[19] Sungkyunkwan Univ, Sch Med, Dept Nucl Med, Samsung Med Ctr, Seoul, South Korea

[20] Seoul Natl Univ, Dept Nucl Med, Coll Med, Seoul Natl Univ Hosp, Seoul, South Korea

[21] Hallym Univ, Coll Med, Dept Internal Med, Chuncheon Sacred Heart Hosp, Chunchon, South Korea

[22] Sejong Gen Hosp, Dept Internal Med, Div Endocrinol & Metab, 28 Hohyeon Ro 489Beon-gil, Bucheon 14754, South Korea

来源：

ENDOCRINOLOGY AND METABOLISM | 2021年 / 36卷 / 02期

关键词：

Pheochromocytoma; Paraganglioma; Diagnosis; Classification; PLASMA-FREE METANEPHRINES; FUNCTIONAL IMAGING MODALITIES; SCALED SCORE PASS; METASTATIC PHEOCHROMOCYTOMA; MALIGNANT PHEOCHROMOCYTOMA; I-123-MIBG SCINTIGRAPHY; GERMLINE MUTATIONS; CHROMOGRANIN-A; SPORADIC PHEOCHROMOCYTOMA/PARAGANGLIOMA; FRACTIONATED METANEPHRINES;

D O I：

10.3803/EnM.2020.908

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pheochromocytoma and paraganglioma (PPGLs) are rare catecholamine-secreting neuroendocrine tumors but can be life-threatening. Although most PPGLs are benign, approximately 10% have metastatic potential. Approximately 40% cases are reported as harboring germline mutations. Therefore, timely and accurate diagnosis of PPGLs is crucial. For more than 130 years, clinical, molecular, biochemical, radiological, and pathological investigations have been rapidly advanced in the field of PPGLs. However, performing diagnostic studies to localize lesions and detect metastatic potential can be still challenging and complicated. Furthermore, great progress on genetics has shifted the paradigm of genetic testing of PPGLs. The Korean PPGL task force team consisting of the Korean Endocrine Society, the Korean Surgical Society, the Korean Society of Nuclear Medicine, the Korean Society of Pathologists, and the Korean Society of Laboratory Medicine has developed this position statement focusing on the comprehensive and updated diagnosis for PPGLs.

引用

页码：322 / 338

页数：17

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