One step hydrothermal functionalization of gold nanoparticles with folic acid

被引:8
作者
Vostrikova, Anna M. [1 ]
Kokorina, Alina A. [1 ]
Mitrophanova, Anastassia N. [1 ]
Sindeeva, Olga A. [1 ]
Sapelkin, Andrei V. [1 ,2 ]
Sukhorukov, Gleb B. [1 ,2 ]
Goryacheva, Irina Y. [1 ]
机构
[1] Saratov NG Chernyshevskii State Univ, Astrakhanskaya 83, Saratov 410012, Russia
[2] Queen Mary Univ London, End Rd, London E1 4NS, England
基金
俄罗斯科学基金会;
关键词
Gold nanoparticles; Folic acid; Biological ligand; Hydrothermal treatment; Functionalization; CARBON DOTS; CANCER; FLUORESCENCE; 6-FORMYLPTERIN; LUMINESCENCE; NANOPROBES; PTERIN;
D O I
10.1016/j.colsurfb.2019.05.072
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A new fundamental concept for one-step in-situ functionalization of gold nanoparticles (GNPs) with folic acid using hydrothermal treatment is described. Hydrothermal treatment has been tuned to increase the light emission from the pterin moiety of folic acid molecule, while retain its structure and functionality, thus providing a simple route to multimodal tags for a variety of in vitro and in vivo biomedical applications. Successful functionalization of GNPs with the biological ligand is confirmed by specific binding with anti-folic acid antibody.
引用
收藏
页码:533 / 538
页数:6
相关论文
共 37 条
[1]   Folic acid targeted Mn:ZnS quantum dots for theranostic applications of cancer cell imaging and therapy [J].
Bwatanglang, Ibrahim Birma ;
Mohammad, Faruq ;
Yusof, Nor Azah ;
Abdullah, Jaafar ;
Hussein, Mohd Zobir ;
Alitheen, Noorjahan Banu ;
Abu, Nadiah .
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2016, 11 :413-428
[2]   Substituent effects on the photophysical properties of pterin derivatives in acidic and alkaline aqueous solutions [J].
Cabrerizo, FM ;
Petroselli, G ;
Lorente, C ;
Capparelli, AL ;
Thomas, AH ;
Braun, AM ;
Oliveros, E .
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2005, 81 (05) :1234-1240
[3]   Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy [J].
Castillo, John J. ;
Rindzevicius, Tomas ;
Rozo, Ciro E. ;
Boisen, Anja .
NANOMATERIALS AND NANOTECHNOLOGY, 2015, 5
[4]   Structural basis for molecular recognition of folic acid by folate receptors [J].
Chen, Chen ;
Ke, Jiyuan ;
Zhou, X. Edward ;
Yi, Wei ;
Brunzelle, Joseph S. ;
Li, Jun ;
Yong, Eu-Leong ;
Xu, H. Eric ;
Melcher, Karsten .
NATURE, 2013, 500 (7463) :486-+
[5]   Folate Conjugated CdHgTe Quantum Dots with High Targeting Affinity and Sensitivity for In vivo Early Tumor Diagnosis [J].
Chen, Haiyan ;
Li, Li ;
Cui, Sisi ;
Mahounga, Dider ;
Zhang, Jun ;
Gu, Yueqing .
JOURNAL OF FLUORESCENCE, 2011, 21 (02) :793-801
[6]   pH-Sensitive Delivery Vehicle Based on Folic Acid-Conjugated Polydopamine-Modified Mesoporous Silica Nanoparticles for Targeted Cancer Therapy [J].
Cheng, Wei ;
Nie, Junpeng ;
Xu, Lv ;
Liang, Chaoyu ;
Peng, Yunmei ;
Liu, Gan ;
Wang, Teng ;
Mei, Lin ;
Huang, Laiqiang ;
Zeng, Xiaowei .
ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (22) :18462-18473
[7]   Gold nanoparticles: Assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology [J].
Daniel, MC ;
Astruc, D .
CHEMICAL REVIEWS, 2004, 104 (01) :293-346
[8]   Augmented Anticancer Activity of a Targeted, Intracellularly Activatable, Theranostic Nanomedicine Based on Fluorescent and Radiolabeled, Methotrexate-Folic Acid-Multiwalled Carbon Nanotube Conjugate [J].
Das, Manasmita ;
Datir, Satyajit R. ;
Singh, Raman Preet ;
Jain, Sanyog .
MOLECULAR PHARMACEUTICS, 2013, 10 (07) :2543-2557
[9]   Full-Color Light-Emitting Carbon Dots with a Surface-State-Controlled Luminescence Mechanism [J].
Ding, Hui ;
Yu, Shang-Bo ;
Wei, Ji-Shi ;
Xiong, Huan-Ming .
ACS NANO, 2016, 10 (01) :484-491
[10]   Gold nanoparticles in biomedical applications: recent advances and perspectives [J].
Dykman, Lev ;
Khlebtsov, Nikolai .
CHEMICAL SOCIETY REVIEWS, 2012, 41 (06) :2256-2282