Relation between amiodarone and desethylamiodarone plasma concentrations and ventricular defibrillation energy requirements

被引：17

作者：

Daoud, EG ^{[1
]}

Man, KC ^{[1
]}

Horwood, L ^{[1
]}

Morady, F ^{[1
]}

Strickberger, SA ^{[1
]}

机构：

[1] UNIV MICHIGAN,DEPT INTERNAL MED,DIV CARDIOL,ANN ARBOR,MI 48109

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1997年 / 79卷 / 01期

关键词：

D O I：

10.1016/S0002-9149(96)00689-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The main finding of this prospective, controlled study is that amiodarone and desethylamiodarone plasma concentrations <1 mg/L are associated with a 23% increase in the acute defibrillation energy requirement and with a 31% increase in the requirement for a subcutaneous patch or array. The defibrillation energy requirement does not correlate with the plasma concentrations of amiodarone, desethylamiodarone, amiodarone plus desethylamiodarone, or with the duration or daily dosage of amiodarone therapy.

引用

页码：97 / &

页数：5

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