Scope of the intramolecular imidotitanium-alkyne [2+2] cycloaddition azatitanetine acylation sequence. An efficient procedure for the synthesis of 2-(2-keto-1-alkylidene)tetrahydropyrrole and related compounds

被引：55

作者：

Fairfax, D ^{[1
]}

Stein, M ^{[1
]}

Livinghouse, T ^{[1
]}

Jensen, M ^{[1
]}

机构：

[1] MONTANA STATE UNIV,DEPT CHEM & BIOCHEM,BOZEMAN,MT 59717

来源：

ORGANOMETALLICS | 1997年 / 16卷 / 08期

关键词：

D O I：

10.1021/om961074f

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Sequential [2 + 2] cycloaddition of transient imidotitanium complexes to tethered alkynes followed by C-acylation of the resulting azatitanetines with acyl cyanides has been shown to provide a range of functionalized tetrahydropyrroles and related derivatives in good to excellent yields. The selectivity of product formation is correlated to the pattern of alkyne substitution.

引用

页码：1523 / 1525

页数：3

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