Viral Noncoding RNAs in Cancer Biology

被引：6
作者：
Li, Zhi [1 ,2 ,3 ]
Fu, Shujun [1 ,2 ,3 ]
Sun, Lun-Quan [1 ,2 ,3 ]
机构：
[1] Cent South Univ, Ctr Mol Med, Xiangya Hosp, Collaborat Innovat Ctr Canc Med, Changsha 410008, Hunan, Peoples R China
[2] Key Lab Mol Radiat Oncol, Changsha, Hunan, Peoples R China
[3] Res Ctr Technol Nucle Acid Based Diagnost & Thera, Changsha, Hunan, Peoples R China
来源：
LONG AND SHORT NONCODING RNAS IN CANCER BIOLOGY | 2016年 / 927卷
关键词：
Oncoviruses; Noncoding RNA; MicroRNAs; Cancer; EPSTEIN-BARR-VIRUS; SARCOMA-ASSOCIATED HERPESVIRUS; POLYADENYLATED NUCLEAR-RNA; LATENCY-ASSOCIATED TRANSCRIPT; ENCODED SMALL RNAS; KAPOSIS-SARCOMA; MESSENGER-RNA; RIG-I; NUCLEOTIDE-SEQUENCE; PROTEIN EXPRESSION;
D O I：
10.1007/978-981-10-1498-7_14
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Over 12 % of all human cancers are caused by oncoviruses, primarily including Epstein-Barr virus (EBV), high-risk human papillomaviruses (HPVs), hepatitis B and C viruses (HBV and HCV, respectively), and Kaposi's sarcoma herpesvirus (KSHV). In addition to viral oncoproteins, a variety of noncoding RNAs (ncRNAs) produced by oncoviruses have been recognized as important cofactors that contribute to the oncogenic events. In this chapter, we will focus on the recent understanding of the long and short noncoding RNAs, as well as microRNAs of the viruses, and discuss their roles in the biology of multistep oncogenesis mediated by established human oncoviruses.
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页码：367 / 389
页数：23
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