Cord blood stem cell transplantation for Diamond-Blackfan anemia

被引：16
作者：
Vettenranta, K
Saarinen, UM
机构：
[1] Div. Hematol.-Oncol. Stem Cell T., Children's Hospital, University of Helsinki
[2] Children's Hospital, University of Helsinki, SF-00290
来源：
BONE MARROW TRANSPLANTATION | 1997年 / 19卷 / 05期
关键词：
cord/placental blood transplant; Diamond-Blackfan anemia;
D O I：
10.1038/sj.bmt.1700675
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Bone marrow transplantation has been successfully employed in the treatment of Diamond-Blackfan anemia (DBA), Transplantation with bone marrow stem cells involves, however, considerable treatment-related toxicity, partially in the form of GVHD, Through the use of cord blood stem cells it may be possible to reduce the risk for both acute and chronic GVHD, although possibly in the face of an increased risk for non-engraftment, We report the successful treatment of a boy with DBA by cord blood stem transplantation from an HLA-identical sibling.
引用
收藏
页码：507 / 508
页数：2
相关论文
共 9 条
  • [1] ALTER BP, 1992, HEMATOLOGY INFANCY C, P216
  • [2] HEMATOPOIETIC RECONSTITUTION IN A PATIENT WITH FANCONIS ANEMIA BY MEANS OF UMBILICAL-CORD BLOOD FROM AN HLA-IDENTICAL SIBLING
    GLUCKMAN, E
    BROXMEYER, HE
    AUERBACH, AD
    FRIEDMAN, HS
    DOUGLAS, GW
    DEVERGIE, A
    ESPEROU, H
    THIERRY, D
    SOCIE, G
    LEHN, P
    COOPER, S
    ENGLISH, D
    KURTZBERG, J
    BARD, J
    BOYSE, EA
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (17) : 1174 - 1178
  • [3] LONG-TERM SURVIVAL AND CURE AFTER MARROW TRANSPLANTATION FOR CONGENITAL HYPOPLASTIC-ANEMIA (DIAMOND-BLACKFAN SYNDROME)
    GREINIX, HT
    STORB, R
    SANDERS, JE
    DEEG, HJ
    DONEY, KC
    SULLIVAN, KM
    WITHERSPOON, RP
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1993, 84 (03) : 515 - 520
  • [4] TRANSPLANTATION OF CORD-BLOOD STEM-CELLS INTO A PATIENT WITH SEVERE THALASSEMIA
    ISSARAGRISIL, S
    VISUTHISAKCHAI, S
    SUVATTE, V
    TANPHAICHITR, VS
    CHANDANAYINGYONG, D
    SCHREINER, T
    KANOKPONGSAKDI, S
    SIRITANARATKUL, N
    PLANKIJAGUM, A
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (06) : 367 - 369
  • [5] Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients
    Kurtzberg, J
    Laughlin, M
    Graham, ML
    Smith, C
    Olson, JF
    Halperin, EC
    Ciocci, G
    Carrier, C
    Stevens, CE
    Rubinstein, P
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (03) : 157 - 166
  • [6] LIPTON JM, 1993, CLIN DISORDERS EXPT, P39
  • [7] MUGISHIMA H, 1995, BONE MARROW TRANSPL, V15, P55
  • [8] ALLOGENEIC SIBLING UMBILICAL-CORD-BLOOD TRANSPLANTATION IN CHILDREN WITH MALIGNANT AND NONMALIGNANT DISEASE
    WAGNER, JE
    KERNAN, NA
    STEINBUCH, M
    BROXMEYER, HE
    GLUCKMAN, E
    [J]. LANCET, 1995, 346 (8969): : 214 - 219
  • [9] Wagner JE, 1996, BLOOD, V88, P795
1