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Restrictive Transfusion Strategy and Clinical Decision Support Practices for Reducing RBC Transfusion Overuse A Laboratory Medicine Best Practice Systematic Review and Meta-Analysis
被引:17
作者:
Derzon, James H.
[1
]
Clarke, Nicole
[2
]
Alford, Aaron
[3
]
Gross, Irwin
[4
]
Shander, Aryeh
[5
]
Thurer, Robert
[6
]
机构:
[1] RTI Int, Res Triangle Pk, NC 27709 USA
[2] Pharmerit Int, Bethesda, MD USA
[3] Natl Network Publ Hlth Inst, Washington, DC USA
[4] Acumen, San Diego, CA USA
[5] Englewood Hosp & Med Ctr, Englewood, NJ USA
[6] Gauss Surg, Los Altos, CA USA
关键词:
Restrictive transfusion strategy;
Computerized physician order entry;
Clinical decision support;
RBC transfusion;
Systematic review;
Meta-analysis;
BLOOD-CELL TRANSFUSION;
PHYSICIAN ORDER ENTRY;
CARDIAC-SURGERY;
OLDER-ADULTS;
MANAGEMENT;
REQUIREMENTS;
TRIAL;
HIP;
OUTCOMES;
CARE;
D O I:
10.1093/ajcp/aqz070
中图分类号:
R36 [病理学];
学科分类号:
100104 ;
摘要:
Objectives: Assess support for the effectiveness of two separate practices, restrictive transfusion strategy and computerized physician order entry/clinical decision support (CPOE/CDS) tools, in decreasing RBC transfusions in adult surgical and nonsurgical patients. Methods: Following the Centers for Disease Control and Prevention Laboratory Medicine Best Practice (LMBP) Systematic Review (A-6) method, studies were assessed for quality and evidence of effectiveness in reducing the percentage of patients transfused and/or units of blood transfused. Results: Twenty-five studies on restrictive transfusion practice and seven studies on CPOE/CDS practice met LMBP inclusion criteria. The overall strength of the body of evidence of effectiveness for restrictive transfusion strategy and CPOE/CDS was rated as high. Conclusions: Based on these procedures, adherence to an institutional restrictive transfusion strategy and use of CPOE/CDS tools for hemoglobin alerts or reminders of the institution's restrictive transfusion policies are effective in reducing RBC transfusion overuse.
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页码:544 / 557
页数:14
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