Restrictive Transfusion Strategy and Clinical Decision Support Practices for Reducing RBC Transfusion Overuse A Laboratory Medicine Best Practice Systematic Review and Meta-Analysis

被引:17
作者
Derzon, James H. [1 ]
Clarke, Nicole [2 ]
Alford, Aaron [3 ]
Gross, Irwin [4 ]
Shander, Aryeh [5 ]
Thurer, Robert [6 ]
机构
[1] RTI Int, Res Triangle Pk, NC 27709 USA
[2] Pharmerit Int, Bethesda, MD USA
[3] Natl Network Publ Hlth Inst, Washington, DC USA
[4] Acumen, San Diego, CA USA
[5] Englewood Hosp & Med Ctr, Englewood, NJ USA
[6] Gauss Surg, Los Altos, CA USA
关键词
Restrictive transfusion strategy; Computerized physician order entry; Clinical decision support; RBC transfusion; Systematic review; Meta-analysis; BLOOD-CELL TRANSFUSION; PHYSICIAN ORDER ENTRY; CARDIAC-SURGERY; OLDER-ADULTS; MANAGEMENT; REQUIREMENTS; TRIAL; HIP; OUTCOMES; CARE;
D O I
10.1093/ajcp/aqz070
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Objectives: Assess support for the effectiveness of two separate practices, restrictive transfusion strategy and computerized physician order entry/clinical decision support (CPOE/CDS) tools, in decreasing RBC transfusions in adult surgical and nonsurgical patients. Methods: Following the Centers for Disease Control and Prevention Laboratory Medicine Best Practice (LMBP) Systematic Review (A-6) method, studies were assessed for quality and evidence of effectiveness in reducing the percentage of patients transfused and/or units of blood transfused. Results: Twenty-five studies on restrictive transfusion practice and seven studies on CPOE/CDS practice met LMBP inclusion criteria. The overall strength of the body of evidence of effectiveness for restrictive transfusion strategy and CPOE/CDS was rated as high. Conclusions: Based on these procedures, adherence to an institutional restrictive transfusion strategy and use of CPOE/CDS tools for hemoglobin alerts or reminders of the institution's restrictive transfusion policies are effective in reducing RBC transfusion overuse.
引用
收藏
页码:544 / 557
页数:14
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