Digital Transformation in Personalized Medicine with Artificial Intelligence and the Internet of Medical Things

被引:36
作者
Lin, Biaoyang [1 ,2 ,3 ]
Wu, Shengjun [4 ]
机构
[1] Zhejiang Univ, Zhejiang Calif Int Nanosyst Inst ZCNI Proprium Re, Hangzhou 310058, Zhejiang, Peoples R China
[2] Zhejiang Univ, Sch Med, Affiliated Hosp 1, Collaborat Innovat Ctr Diag & Treatment Infect Di, Hangzhou, Peoples R China
[3] Univ Washington, Sch Med, Dept Urol, Seattle, WA 98195 USA
[4] Zhejiang Univ, Sch Med, Sir Run Run Shaw Hosp, Dept Clin Labs, Hangzhou, Peoples R China
关键词
digital health; artificial intelligence; machine learning; deep phenotyping; Internet of Medical Things; personalized medicine; theranostics;
D O I
10.1089/omi.2021.0037
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Digital transformation is impacting every facet of science and society, not least because there is a growing need for digital services and products with the COVID-19 pandemic. But the need for digital transformation in diagnostics and personalized medicine field cuts deeper. In the past, personalized/precision medicine initiatives have been unable to capture the patients' experiences and clinical outcomes in real-time and in real-world settings. The availability of wearable smart sensors, wireless connectivity, artificial intelligence, and the Internet of Medical Things is changing the personalized/precision medicine research and implementation landscape. Digital transformation in poised to accelerate personalized/precision medicine and systems science in multiple fronts such as deep real-time phenotyping with patient-reported outcomes, high-throughput association studies between omics and highly granular phenotypic variation, digital clinical trials, among others. The present expert review offers an analysis of these systems science frontiers with a view to future applications at the intersection of digital health and personalized medicine, or put in other words, signaling the rise of "digital personalized medicine."
引用
收藏
页码:77 / 81
页数:5
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