Compensation for cures: Why we should pay a premium for participation in 'challenge studies'

被引：20

作者：

Anomaly, Jonathan ^{[1
]}

Savulescu, Julian ^{[2
]}

机构：

[1] Univ Calif San Diego, Inst Pract Eth, 9500 Gilman Dr, La Jolla, CA 92093 USA

[2] Univ Oxford, Uehiro Ctr Pract Eth, Suite 8,Littlegate House16-17,St Ebbes St, Oxford OX1 1PT, England

来源：

BIOETHICS | 2019年 / 33卷 / 07期

关键词：

antibiotic resistance; antibiotics; challenge studies; consent; phage therapy;

D O I：

10.1111/bioe.12596

中图分类号：

B82 [伦理学（道德学）];

学科分类号：

摘要：

Antibiotic resistance is one of the most pressing public health problems humanity faces. Research into new classes of antibiotics and new kinds of treatments - including risky experimental treatments such as phage therapy and vaccines - is an important part of improving our ability to treat infectious diseases. In order to aid this research, we will argue that we should permit researchers to pay people any amount of money to compensate for the risks of participating in clinical trials, including 'challenge studies' that involve deliberately infecting patients. We think that standard worries about paying for participation in risky research are reducible to concerns that can be addressed with the right screening mechanisms.

引用

页码：792 / 797

页数：6

共 23 条

[1]

ANDERSON ES, 1990, PHILOS PUBLIC AFF, V19, P71

[2]

Anomaly J., 2014, U. Queensland LJ, V33, P263

[3]

[Anonymous], 2015, MARKETS LIMITS MORAL

[4] Ethical Criteria for Human Challenge Studies in Infectious Diseases [J].

Bambery, Ben ;

Selgelid, Michael ;

Weijer, Charles ;

Savulescu, Julian ;

Pollard, Andrew J. .

PUBLIC HEALTH ETHICS, 2016, 9 (01) :92-103

[5]

Crawford DorothyH., 2009, Deadly Companions: How Microbes Shaped Our History

[6] Informative inducement: Study payment as a signal of risk [J].

Cryder, Cynthia E. ;

London, Alex John ;

Volpp, Kevin G. ;

Loewenstein, George .

SOCIAL SCIENCE & MEDICINE, 2010, 70 (03) :455-464

[7] The expanding vaccine development pipeline, 1995-2008 [J].

Davis, Matthew M. ;

Butchart, Amy T. ;

Coleman, Margaret S. ;

Singer, Dianne C. ;

Wheeler, John R. C. ;

Pok, Angela ;

Freed, Gary L. .

VACCINE, 2010, 28 (05) :1353-1356

[8]

Emanuel E.J., 2008, OXFORD TXB CLIN RES, P123

[9]

Grady C., 2001, AM J BIOETHICS, V1, P43

[10] Empirical assessment of whether moderate payments are undue or unjust inducements for participation in clinical trials [J].

Halpern, SD ;

Karlawish, JHT ;

Casarett, D ;

Berlin, JA ;

Asch, DA .

ARCHIVES OF INTERNAL MEDICINE, 2004, 164 (07) :801-803

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