Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork

被引:426
|
作者
Hertweck, Christian
Luzhetskyy, Andriy
Rebets, Yuri
Bechthold, Andreas
机构
[1] Univ Freiburg, Inst Pharmazeut Wissensch Pharmazeut Biol & Biote, D-79104 Freiburg, Germany
[2] HKI, Leibniz Inst Nat Prod Res & Infect Biol, D-07745 Jena, Germany
关键词
D O I
10.1039/b507395m
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review covers advances in understanding of the biosynthesis of polyketides produced by type II PKS systems at the genetic, biochemical and structural levels.
引用
收藏
页码:162 / 190
页数:29
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