Quantitative analysis of gadoxetic acid-enhanced magnetic resonance imaging predicts histological grade of hepatocellular carcinoma

被引：11
作者：
Tong, Hong-fei [1 ]
Liang, Hong-bo [1 ]
Mo, Zhi-kang [1 ]
Guan, Tian-pei [1 ]
Yang, Jian [1 ]
Fang, Chi-hua [1 ]
机构：
[1] Southern Med Univ, ZhuJiang Hosp, Dept Hepatobiliary Surg, 253 Ind Rd, Guangzhou 510282, Guangdong, Peoples R China
来源：
CLINICAL IMAGING | 2017年 / 43卷
关键词：
Hepatocellular carcinoma; Gd-EOB-DTPA; MRI; Histological grade; Quantitative analysis; GD-EOB-DTPA; HISTOPATHOLOGIC FINDINGS; CONTRAST AGENT; SPIRAL CT; LIVER; MRI; DIAGNOSIS; EFFICACY; SAFETY;
D O I：
10.1016/j.clinimag.2016.12.009
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Objective: To confirm the histological grade of hepatocellular carcinoma (HCC) by gadoxetic acid-enhanced MRI. Methods: Ninety-five HCC patients underwent gadoxetic acid-enhanced MRI before surgical intervention. The correlations among the signal absolute enhancement, contrast enhancement ratio (CER) and tumor histological grade were analyzed. Results: The correlation between CER of tumor-to-liver and the grades of tumor differentiation is the most significant negative. The k-value for the CER of tumor-to-liver and histopathologic analysis is 0.62, which gives evidence of good agreement. Conclusion: The quantitative analysis of gadoxetic acid-enhanced MRI can predict the histological grades of small HCCs. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码：9 / 14
页数：6
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