Transgenerational Inheritance: Perpetuating RNAi

被引：3
作者：
Brown, Kristen C. [1 ,2 ]
Montgomery, Taiowa A. [1 ]
机构：
[1] Colorado State Univ, Dept Biol, Ft Collins, CO 80523 USA
[2] Colorado State Univ, Cell & Mol Biol Program, Ft Collins, CO 80523 USA
来源：
CURRENT BIOLOGY | 2017年 / 27卷 / 10期
关键词：
C; ELEGANS; CAENORHABDITIS-ELEGANS; EPIGENETIC MEMORY; PIRNAS; GERMLINE; METHYLATION; IMMORTALITY; TRIGGER; SIRNAS;
D O I：
10.1016/j.cub.2017.03.061
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Reversiblechanges in gene expression independent of the genetic code can be transmitted from one generation to the next via poorly understood mechanisms. In worms, a histone-modifying enzyme is necessary to keep small RNA-guided transgenerational gene silencing in check.
引用
收藏
页码：R383 / R385
页数：4
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