Liver gene therapy and hepatocellular carcinoma: A complex web

被引:21
作者
de Jong, Ype P. [1 ,2 ]
Herzog, Roland W.
机构
[1] Weill Cornell Med, Div Gastroenterol & Hepatol, New York, NY 10065 USA
[2] Rockefeller Univ, Lab Virol & Infect Dis, New York, NY 10065 USA
关键词
D O I
10.1016/j.ymthe.2021.03.009
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:1353 / 1354
页数:2
相关论文
共 6 条
[1]   AAV Joins the Rank of Genotoxic Vectors [J].
Dave, Utpal P. ;
Cornetta, Kenneth .
MOLECULAR THERAPY, 2021, 29 (02) :418-419
[2]   Long-Term Follow-Up of the First in Human Intravascular Delivery of AAV for Gene Transfer: AAV2-hFIX16 for Severe Hemophilia B [J].
George, Lindsey A. ;
Ragni, Margaret, V ;
Rasko, John E. J. ;
Raffini, Leslie J. ;
Samelson-Jones, Benjamin J. ;
Ozelo, Margareth ;
Hazbon, Maria ;
Runowski, Alexa R. ;
Wellman, Jennifer A. ;
Wachtel, Katie ;
Chen, Yifeng ;
Anguela, Xavier M. ;
Kuranda, Klaudia ;
Mingozzi, Federico ;
High, Katherine A. .
MOLECULAR THERAPY, 2020, 28 (09) :2073-2082
[3]   Increased Risk for Hepatocellular Carcinoma Persists Up to 10 Years After HCV Eradication in Patients With Baseline Cirrhosis or High FIB-4 Scores [J].
Ioannou, George N. ;
Beste, Lauren A. ;
Green, Pamela K. ;
Singal, Amit G. ;
Tapper, Elliot B. ;
Waljee, Akbar K. ;
Sterling, Richard K. ;
Feld, Jordan J. ;
Kaplan, David E. ;
Taddei, Tamar H. ;
Berry, Kristin .
GASTROENTEROLOGY, 2019, 157 (05) :1264-+
[4]   Adeno-associated virus in the liver: natural history and consequences in tumour development [J].
La Bella, Tiziana ;
Imbeaud, Sandrine ;
Peneau, Camille ;
Mami, Iadh ;
Datta, Shalini ;
Bayard, Quentin ;
Caruso, Stefano ;
Hirsch, Theo Z. ;
Calderaro, Julien ;
Morcrette, Guillaume ;
Guettier, Catherine ;
Paradis, Valerie ;
Amaddeo, Giuliana ;
Laurent, Alexis ;
Possenti, Laurent ;
Chiche, Laurence ;
Bioulac-Sage, Paulette ;
Blanc, Jean-Frederic ;
Letouze, Eric ;
Nault, Jean-Charles ;
Zucman-Rossi, Jessica .
GUT, 2020, 69 (04) :737-747
[5]   Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas [J].
Nault, Jean-Charles ;
Datta, Shalini ;
Imbeaud, Sandrine ;
Franconi, Andrea ;
Mallet, Maxime ;
Couchy, Gabrielle ;
Letouze, Eric ;
Pilati, Camilla ;
Verret, Benjamin ;
Blanc, Jean-Frederic ;
Balabaud, Charles ;
Calderaro, Julien ;
Laurent, Alexis ;
Letexier, Melanie ;
Bioulac-Sage, Paulette ;
Calvo, Fabien ;
Zucman-Rossi, Jessica .
NATURE GENETICS, 2015, 47 (10) :1187-+
[6]   A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells [J].
Nguyen, Giang N. ;
Everett, John K. ;
Kafle, Samita ;
Roche, Aoife M. ;
Raymond, Hayley E. ;
Leiby, Jacob ;
Wood, Christian ;
Assenmacher, Charles-Antoine ;
Merricks, Elizabeth P. ;
Long, C. Tyler ;
Kazazian, Haig H. ;
Nichols, Timothy C. ;
Bushman, Frederic D. ;
Sabatino, Denise E. .
NATURE BIOTECHNOLOGY, 2021, 39 (01) :47-55