Barriers to genetic testing in newly diagnosed breast cancer patients: Do surgeons limit testing?

被引：26

作者：

Hafertepen, Laura ^{[1
,2
]}

Pastorino, Alyssa ^{[1
]}

Morman, Nichole ^{[1
]}

Snow, Jennifer ^{[1
,3
]}

Halaharvi, Deepa ^{[1
]}

Byrne, Lindsey ^{[1
,4
]}

Cripe, Mark ^{[1
]}

机构：

[1] Grant Med Ctr, OhioHlth Breast & Canc Surg, Columbus, OH 43215 USA

[2] SurgOne PC, 3333 South Bannock St,350, Englewood, CO 80110 USA

[3] Texas Breast Specialists, 191 Walls Dr, Cleburne, TX 76033 USA

[4] Mt Carmel Canc Genet Program, 5969 East Broad St,Suite 102, Columbus, OH 43213 USA

来源：

AMERICAN JOURNAL OF SURGERY | 2017年 / 214卷 / 01期

关键词：

Breast cancer; BRCA1; BRCA2; Genetic counseling; Genetic testing; BRCA2 MUTATION CARRIERS; RISK;

D O I：

10.1016/j.amjsurg.2016.08.012

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

BACKGROUND: Genetic testing results influence treatment recommendations in newly diagnosed breast cancer patients. However, at-risk patients do not uniformly undergo genetic testing. The goal of this study was to identify barriers to genetic testing in newly diagnosed breast cancer patients. METHODS: A prospective database of newly diagnosed breast cancer patients meeting specific criteria over an 18-month period was created and retrospectively reviewed. RESULTS: A total of 532 patients were identified at risk for genetic mutation. Of these 313 (59%) patients completed a genetic counseling appointment and 292 (55%) underwent genetic testing. One hundred seven (24%) were never referred to genetic counselors and 89 (17%) were referred but did not complete an appointment. Patients referred to genetics were younger than the nonreferred patients (50.9 vs 60.6 years, P < .001). The 89 women referred to genetics who did not complete an appointment were surveyed and had varied reasons for not completing an appointment. CONCLUSIONS: The largest barrier to genetic testing was lack of physician referral; therefore, provider education must be improved. Appointments should be convenient and providers should proactively discuss the significant implications of testing results. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：105 / 110

页数：6

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