A Research on Bioinformatics Prediction of Protein Subcellular Localization

被引：1

作者：

Fang, Gang ^{[1
]}

Tao, Guirong ^{[1
]}

Zhang, Shemin ^{[2
]}

机构：

[1] Xian Univ Arts & Sci, Dept Life Sci, Xian 710065, Peoples R China

[2] Shaanxi Univ Technol, Dept Comp Sci, Hanzhong 723000, Peoples R China

来源：

CURRENT BIOINFORMATICS | 2009年 / 4卷 / 03期

关键词：

Bioinformatics; prediction; protein subcellular localization; localizome; proteomics; database; GRAM-NEGATIVE BACTERIA; AMINO-ACID-COMPOSITION; SUPPORT VECTOR MACHINES; BUDDING YEAST; DATABASE; SEQUENCE; LOCATION; SYSTEM; PEPTIDES; SIGNALS;

D O I：

10.2174/157489309789071084

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Protein subcellular localization is one of the key characteristic to understand its biological function. Proteins are transported to specific organelles and suborganelles after they are synthesized. They take part in cell activity and function efficiently when correctly localized. Inaccurate subcellular localization will have great impact on cellular function. Prediction of protein subcellular localization is one of the important areas in protein function research. Now it becomes the hot issue in bioinformatics. In this review paper, the recent progress on bioinformatics research of protein subcellular localization and its prospect are discussed.

引用

页码：177 / 182

页数：6

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