Study of a High-Risk Group of Stage II Colon Cancer

被引：0

作者：

Hirosawa, Tomoichiro ^{[1
]}

Itabashi, Michio ^{[1
]}

Bamba, Yoshiko ^{[1
]}

Ogawa, Shinpei ^{[1
]}

Sirotani, Noriyasu ^{[1
]}

Kameoka, Shingo ^{[1
]}

机构：

[1] Tokyo Womens Med Univ, Dept Surg 2, Sch Med, Sinjuku Ku, Tokyo 1628666, Japan

来源：

INTERNATIONAL SURGERY | 2009年 / 94卷 / 02期

关键词：

Colon cancer; Stage II; Adjuvant chemotherapy; RECTAL-CANCER; EFFICACY; FLUOROURACIL; TRIAL;

D O I：

暂无

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

This study was conducted for the purpose of identifying a high-risk group for recurrence of stage II colon cancer and determine those cases for which postoperative adjuvant chemotherapy for stage II colon cancer is indicated. The subjects of this study consisted of 179 stage II cases and 114 stage IIIa cases among 462 surgical colon cancer cases examined at this department from January 1, 1991 to December 31, 1996 classified as A for the degree of cure, with the exception of m cancer. A nonrecurrence group and a recurrence group of stage II and stage IIIa colon cancer cases were compared on the basis of parameters. Gender, age, and lymph ducts were extracted from multivariate analysis, while age and lymph ducts were extracted from a survival analysis using the Cox proportional hazard model. A high-risk group for recurrence of stage II colon cancer was determined to consist of young men of ly 2.3. Since the nonrecurrence survival rates and survival prognoses of ly 2.3 cases in particular were equivalent to those of stage IIIa, this is considered to be a risk factor for recurrence of stage II colon cancer, and postoperative chemotherapy is believed to be indicated.

引用

页码：130 / 135

页数：6

共 15 条

[11]

LABIANCA R, 1995, LANCET, V345, P939

[12]

Sobin L.H., 2009, UICC: TNM classification of malignant tumors, V7th

[13]

TSUBAKI M, 1992, J JAP SOC GASTROENTE, V24, P2190

[14] Clinical trial to assess the relative efficacy of fluorouracil and leucovorin, fluorouracil and levamisole, and fluorouracil, leucovorin, and levamisole in patients with Dukes' B and C carcinoma of the colon: Results from national surgical adjuvant breast and bowel project C-04 [J].

Wolmark, N ;

Rockette, H ;

Mamounas, E ;

Jones, J ;

Wieand, S ;

Wickerham, DL ;

Bear, HD ;

Atkins, JN ;

Dimitrov, NV ;

Glass, AG ;

Fisher, ER ;

Fisher, B .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (11) :3553-3559

[15]

YUGAWA K, 2003, J JAP SOC GASTROENTE, V36, P1651

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