Design, synthesis and evaluation of extended heterocycle linked C81C8′ pyrrolo[2,1-c][1,4]benzodiazepine DNA cross-linking agents

被引:0
作者
Howard, P. W.
Tiberghien, A.
Gregson, S. J.
Kang, G. -D.
Stephenson, M.
Kiakos, K.
Klee, S.
Hartley, J. M.
Hartley, J. A.
Thurston, D. E.
机构
[1] Spirogen Ltd, London, England
[2] UCL, Dept Oncol, London, England
[3] Univ London, Sch Pharm, Dept Pharmaceut & Biol Chem, London WC1N 1AX, England
来源
EJC SUPPLEMENTS | 2006年 / 4卷 / 12期
关键词
D O I
10.1016/S1359-6349(06)70301-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
296
引用
收藏
页码:93 / 93
页数:1
相关论文
共 50 条
[41]   SYNTHESIS OF DNA-INTERACTIVE PYRROLO[2,1-C][1,4]BENZODIAZEPINES [J].
THURSTON, DE ;
BOSE, DS .
CHEMICAL REVIEWS, 1994, 94 (02) :433-465
[42]   A convenient synthesis of pyrrolo[2,1-c][1,4]benzoxazines [J].
Sánchez, I ;
Pujol, MD .
TETRAHEDRON, 1999, 55 (17) :5593-5598
[43]   Design, Synthesis and Biological Evaluation of Pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione Derivatives as Novel Neuroprotective Agents [J].
Quan, Jishun ;
Zhang, Dongping ;
Zhang, Zhuo ;
Wang, Jian ;
Ma, Chao ;
Cheng, Maosheng .
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2021, 37 (03) :647-654
[44]   Design, Synthesis and Biological Evaluation of Pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione Derivatives as Novel Neuroprotective Agents [J].
Jishun Quan ;
Dongping Zhang ;
Zhuo Zhang ;
Jian Wang ;
Chao Ma ;
Maosheng Cheng .
Chemical Research in Chinese Universities, 2021, 37 :647-654
[45]   Spectroscopic and calorimetric studies on the DNA recognition of pyrrolo[2,1-c][1,4]benzodiazepine hybrids [J].
Rettig, Michael ;
Kamal, Ahmed ;
Ramu, R. ;
Mikolajczak, Judith ;
Weisz, Klaus .
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (02) :919-928
[46]   Pyrrolo[2,1-c][1,4]benzodiazepine-5,11-dithione [J].
Ourahou, Sarah ;
Zouihri, Hafid ;
Essassi, El Mokhtar ;
Ng, Seik Weng .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 :O1653-U128
[47]   Synthesis, DNA binding, and cytotoxicity studies of pyrrolo [2,1-c][1,4]benzodiazepine-anthraquinone conjugates [J].
Kamal, Ahmed ;
Ramu, R. ;
Tekumalla, Venkatesh ;
Khanna, G. B. Ramesh ;
Barkume, Madan S. ;
Juvekar, Aarti S. ;
Zingde, Surekha M. .
BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (22) :6868-6875
[48]   Synthesis and DNA-binding ability of pyrrolo[2,1-c][1,4]benzodiazepine-azepane conjugates [J].
Kamal, A ;
Reddy, DR ;
Reddy, PSMM ;
Rajendar .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (05) :1160-1163
[49]   Parallel synthesis of a novel C2-aryl pyrrolo[2,1-c][1,4]benzodiazepine (PBD) library [J].
Antonow, Dyeison ;
Cooper, Nectaroula ;
Howard, Philip W. ;
Thurston, David E. .
JOURNAL OF COMBINATORIAL CHEMISTRY, 2007, 9 (03) :437-445
[50]   Pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates.: Synthesis, DNA binding and cytotoxicity [J].
Kamal, A ;
Ramu, R ;
Khanna, GBR ;
Saxena, AK ;
Shanmugavel, M ;
Pandita, RM .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (19) :4907-4909