Perhydropyrrolo[1,2-A]indole synthesis: Diastereoselection in an intramolecular conjugate addition of an amine to a 1,4-cyclohexadienone

被引：12
作者：
Bland, D [1 ]
Hart, DJ [1 ]
Lacoutiere, S [1 ]
机构：
[1] OHIO STATE UNIV,DEPT CHEM,COLUMBUS,OH 43210
来源：
TETRAHEDRON | 1997年 / 53卷 / 26期
关键词：
D O I：
10.1016/S0040-4020(97)90397-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Cyclization of amino-cyclohexadienone 4 occurs with a high level of diastereoselection to afford perhydroindole 13. The relationship of this observation to controlling the relative stereochemistry between C-34 and other stereogenic centers in the manzamine family of alkaloids is discussed. (C) 1997 Elsevier Science Ltd.
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页码：8871 / 8880
页数：10
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