Non-nucleoside reverse transcriptase inhibitors: a review

被引：43
作者：
Waters, L.
John, L.
Nelson, M.
机构：
[1] Chelsea & Westminster Hosp, Dept Infect Dis, London, England
[2] Chelsea & Westminster Hosp, Dept HIV GU Med, London, England
来源：
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE | 2007年 / 61卷 / 01期
关键词：
D O I：
10.1111/j.1742-1241.2006.01146.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Non-nucleoside reverse transcriptase inhibitors form the backbone of antiretroviral treatment for many HIV-infected individuals. The tolerability, pill burden and efficacy associated with this class of agents make them a frequent choice for first-line therapy. Here we review nevirapine and efavirenz in terms of efficacy, resistance and toxicity, focusing particularly on the use of nevirapine to prevent mother-to-child transmission in developing countries.
引用
收藏
页码：105 / 118
页数：14
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