Molecular Dynamic Simulations Suggest Novel PIP2 Binding Sites for SK2 Channel Regulation

被引：0
|
作者：
Srivatsa, Adith V. [1 ]
Woltz, Ryan L. [2 ]
Nguyen, Phuong T. [3 ]
DeMarco, Kevin [4 ]
Zhang, Xiao-Dong [5 ]
Vorobyov, Igor V. [6 ]
Yarov-Yarovoy, Vladimir [6 ]
Chiamvimonvat, Nipavan [2 ]
机构：
[1] Georgia Inst Technol, Biomed Engn, Atlanta, GA 30332 USA
[2] Univ Calif Davis, Internal Med, Davis, CA 95616 USA
[3] Univ Calif Davis, Biophys Grad Grp, Davis, CA 95616 USA
[4] Univ Calif Davis, Davis, CA 95616 USA
[5] Univ Calif Davis, Dept Mol & Cellular Biol, Davis, CA 95616 USA
[6] Univ Calif Davis, Dept Physiol & Membrane Biol, Davis, CA 95616 USA
来源：
BIOPHYSICAL JOURNAL | 2021年 / 120卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
1100-Pos
引用
收藏
页码：227A / 227A
页数：1
相关论文
共 50 条
  • [21] Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation
    Nicholas J. Sisco
    Cole V. M. Helsell
    Wade D. Van Horn
    Scientific Reports, 9
  • [22] Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation
    Sisco, Nicholas J.
    Helsell, Cole V. M.
    Van Horn, Wade D.
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [23] Effects of PIP2 Binding to its Different Binding Sites on ANO1 Function
    Yu, Kuai
    Jiang, Tao
    Cui, Yuanyuan
    Tajkhorshid, Emad
    Hartzell, H. Criss
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 419A - 419A
  • [24] Cooperative Regulation of Slack Channel by Na+, Cl- and PIP2
    Zhang, Zhe
    Tang, Qiongyao
    Logothetis, Diomedes E.
    BIOPHYSICAL JOURNAL, 2012, 102 (03) : 136A - 136A
  • [25] CELL-SPECIFIC ROLE OF PIP2 IN GIRK CHANNEL REGULATION BY RECEPTORS
    Ho, Won-Kyung
    Lee, Suk-Ho
    Sohn, Jong-Woo
    Cho, Hana
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, 59 : 92 - 92
  • [26] A universal tool for investigating ion channel regulation by PIP2 in cardiac myocytes
    Hertel, F.
    Switalski, A.
    Bender, K.
    Kienitz, M-C
    Pott, L.
    CARDIOVASCULAR RESEARCH, 2010, 87 : S104 - S104
  • [27] Pip2-Channel Interaction as a Critical Element in Regulation of SK Channel Activity
    Zhang, Miao
    Cui, Meng
    Meng, Xuan-Yu
    Zhang, Ji-Fang
    Logothetis, Diomedes E.
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 749A - 749A
  • [28] The biological function of PIP2 clustering in enzyme activation and ion channel regulation
    Hansen, Scott B.
    Pavel, Mahmud Arif
    Petersen, E. Nicholas
    FASEB JOURNAL, 2019, 33
  • [29] A PIP2 Binding Site on a Human TRP Channel: Simulation Studies of PKD2
    Wang, Qinrui
    Hedger, George
    Aryal, Prafulla
    Shi, Jiye
    Carpenter, Elizabeth P.
    Sansom, Mark S. P.
    BIOPHYSICAL JOURNAL, 2018, 114 (03) : 397A - 397A
  • [30] Roles of PIP2 in the membrane binding of MIM I-BAR: insights from molecular dynamics simulations
    Lin, Xubo
    Wang, Hongyin
    Lou, Zhichao
    Cao, Meng
    Zhang, Zuoheng
    Gu, Ning
    FEBS LETTERS, 2018, 592 (15): : 2533 - 2542
12345