Clinic and demographic characteristics of pediatric patients with Lichen sclerosus

被引:7
作者
Akbas, Ayse [1 ]
Kilinc, Fadime [1 ]
机构
[1] Minist Hlth Ankara City Hosp, Dept Dermatol, Ankara, Turkey
关键词
child; epidemiology; extragenital; genital; lichen sclerosus; BORRELIA-BURGDORFERI; DERMATOLOGISTS GUIDELINES; RETROSPECTIVE ANALYSIS; BRITISH ASSOCIATION; ET-ATROPHICUS; VULVAR; CHILDHOOD; CHILDREN; MORPHEA; CORTICOSTEROIDS;
D O I
10.24953/turkjped.2021.01.015
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background. Lichen sclerosus (LS) is a chronic disease of the skin, for which the pathogenesis is not known. It can lead to various changes of the skin and the genital area, potentially leading to both functional as well as cosmetic problems for the patient, thus disrupting the quality of life. In this study; the purpose was to review the clinical characteristics and the treatments of the 15 pediatric patients under the age of 18 followed up in our out-patient clinic with a diagnosis of LS and to compare the findings with literature data. Methods. Between 2011 and 2017, the files of 15 patients diagnosed clinically and/or histologically with LS in our clinic were retrospectively examined. The demographic characteristics, clinic and laboratory findings, treatment options of the patients are reported. Results. Of the patients included in the study 14 were girls and one was a boy. The average age was 11.6 years (5-17 years), the average age for the initial disease was 7.8 years (2-13 years). The average duration of the disease at the diagnosis was 3.9 years. The most common form was genital vulvar type (8/14 girls) without anal and cutaneous involvement, and each of them suffered from itching. One of the cases had genital LS as well as extragenital morphea lesions. Two of the 15 patients were ANA positive. The other antibodies were negative. In two cases with extragenital involvement, lesions were widespread and they were in blachkoid form. Conclusion. LS is a chronic disease that progresses with recurrences and regressions. In our study, the most common LS type was genital type (60%). There was extragenital involvement in 6 patients (40%). Extragenital involvement was the most common on the trunk. Diagnosis, treatment and follow-up during childhood is highly important to prevent any possible future anatomical or psychological damage and genital malignancies.
引用
收藏
页码:126 / 135
页数:10
相关论文
共 50 条
[31]   GENITAL LICHEN-SCLEROSUS (LICHEN-SCLEROSUS-ET-ATROPHICUS) IN CHILDHOOD AND ADOLESCENCE [J].
RIDLEY, CM .
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 1993, 86 (02) :69-75
[32]   EMAS clinical guide: Vulvar lichen sclerosus in peri and postmenopausal women [J].
Perez-Lopez, Faustino R. ;
Ceausu, Iuliana ;
Depypere, Herman ;
Erel, C. Tamer ;
Lambrinoudaki, Irene ;
Rees, Margaret ;
Schenck-Gustafsson, Karin ;
Tremollieres, Florence ;
van der Schouw, Yvonne T. ;
Simoncini, Tommaso .
MATURITAS, 2013, 74 (03) :279-282
[33]   Extragenital Bullous Lichen Sclerosus in a Pediatric Patient: A Case Report and Literature Review [J].
Shiver, Mallory ;
Papasakelariou, Catherine ;
Brown, Jameel Ahmad ;
Wirges, Marla ;
Kincannon, Jay .
PEDIATRIC DERMATOLOGY, 2014, 31 (03) :383-385
[34]   Lichen sclerosus [J].
Yesudian, PD ;
Sugunendran, H ;
Bates, CM ;
O'Mahony, C .
INTERNATIONAL JOURNAL OF STD & AIDS, 2005, 16 (07) :465-474
[35]   Lichen sclerosus [J].
Jablonowska, Olga ;
Wozniacka, Anna ;
Zebrowska, Agnieszka .
PRZEGLAD DERMATOLOGICZNY, 2021, 108 (02) :126-136
[36]   Lichen Sclerosus [J].
Ergin, Seniz .
TURK DERMATOLOJI DERGISI-TURKISH JOURNAL OF DERMATOLOGY, 2012, 6 (02) :27-34
[37]   Lichen Sclerosus [J].
Consolmagno, Lynn .
JOURNAL OF THE DERMATOLOGY NURSES ASSOCIATION, 2013, 5 (04) :213-216
[38]   Lichen sclerosus in the genitourinary region [J].
Hofer, C. ;
Koehn, F. -M. ;
Hatzichristodoulou, G. S. ;
Gschwend, J. E. ;
Treiber, U. .
UROLOGE, 2011, 50 (10) :1291-1296
[39]   Lichen sclerosus in children and adolescents [J].
Dendrinos, Melina L. ;
Quint, Elisabeth H. .
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2013, 25 (05) :370-374
[40]   Obstructive complications of lichen sclerosus [J].
Christman, Matthew S. ;
Chen, Jamesina T. ;
Holmes, Nicholas M. .
JOURNAL OF PEDIATRIC UROLOGY, 2009, 5 (03) :165-169