An adult case suggestive of pediatric autoimmune neuropsychiatric disor- ders associated with streptococcal infection (PANDAS) diagnosis

被引:0
作者
Aydin, Sare [1 ]
Savas, Ahmet Ekrem [1 ]
Aslan, Esma Akpinar [1 ]
Batmaz, Sedat [2 ]
机构
[1] Tokat Gaziosmanpasa Univ, Ruh Sagligi & Hastaliklari Ana Bilim Dali, Tip Fak, Tokat, Turkey
[2] Ankara Sosyal Bilimler Univ, Sosyal & Beseri Bilimler Fak, Psikol Bolumu, Ankara, Turkey
来源
KLINIK PSIKIYATRI DERGISI-TURKISH JOURNAL OF CLINICAL PSYCHIATRY | 2022年 / 25卷 / 04期
关键词
PANDAS; tic disorder; obsessive compulsive disorder; neuropsychiatric disorders; OBSESSIVE-COMPULSIVE DISORDER; CHILDREN;
D O I
10.5505/kpd.2022.16768
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Pediatric autoimmune neuropsychiatric disorders associ-ated with streptococcal infection (PANDAS) describe a picture with obsessive-compulsive symptoms and tics in childhood as a result of autoimmune response after group A-beta hemolytic streptococcal infection. PANDAS is a syndrome which progresses with various symptoms in childhood and is difficult to diagnose, and in which a significant regression in neuropsychiatric symptoms is observed with early detection and treatment of infec-tion. In this article, a 21-year-old case with OCD findings and tics exacerbated by recurrent infections, suggesting the diagnosis of PANDAS is presented. Undiagnosed and untreated PANDAS has a high risk of becoming chronic and transforming into lifelong obsessive compulsive di-sorder and tic disorder. Patients who are thought to have a diagnosis of PANDAS should be referred to the appro-priate center without delay and treatment should be started.
引用
收藏
页码:434 / 440
页数:7
相关论文
共 19 条
[1]  
American Psychiatric Association, 2013, DIAGN STAT MAN MENT, DOI DOI 10.1176/APPI.BOOKS.9780890425596
[2]  
Bayraktar E, 2000, KLIN PSIKOFARMAKOL B, V10, P144
[3]   The question of PANDAS in adults [J].
Bodner, SM ;
Morshed, SA ;
Peterson, BS .
BIOLOGICAL PSYCHIATRY, 2001, 49 (09) :807-810
[4]   Incidence of anti-brain antibodies in children with obsessive-compulsive disorder [J].
Dale, RC ;
Heyman, I ;
Giovannoni, G ;
Church, AJ .
BRITISH JOURNAL OF PSYCHIATRY, 2005, 187 :314-319
[5]   Psychiatric disorders in first-degree relatives of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) [J].
Lougee, L ;
Perlmutter, SJ ;
Nicolson, R ;
Garvey, MA ;
Swedo, SE .
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2000, 39 (09) :1120-1126
[6]  
Macerollo A, 2013, TREMOR OTHER HYPERK, V3
[7]   Late-onset PANDAS syndrome with abdominal muscle involvement [J].
Martinelli, P ;
Ambrosetto, G ;
Minguzzi, E ;
Battaglia, S ;
Rizzo, G ;
Scaglione, C .
EUROPEAN NEUROLOGY, 2002, 48 (01) :49-51
[8]  
Mirza HC, 2015, TURK MIKROBIYOLOJI C, V45, P109
[9]   Prospective identification and treatment of children with pediatric autoimmune neuropsychiatric disorder associated with group A streptococcal infection (PANDAS) [J].
Murphy, ML ;
Pichichero, ME .
ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 2002, 156 (04) :356-361
[10]   Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood [J].
Perlmutter, SJ ;
Leitman, SF ;
Garvey, MA ;
Hamburger, S ;
Feldman, E ;
Leonard, HL ;
Swedo, SE .
LANCET, 1999, 354 (9185) :1153-1158