Transition-metal-free N-arylation: A general approach to aza-fused poly-heteroaromatics

被引：12

作者：

Annareddygari, Srikanth ^{[1
,2
]}

Kasireddy, Venkateshwer Reddy ^{[1
,3
]}

Reddy, Jayachandra ^{[2
]}

机构：

[1] Jawaharlal Nehru Technol Univ, Dept Chem, Coll Engn, Hyderabad 500085, India

[2] Dr JCR BIOSCEIENCES PRIVATE Ltd, Dept Res & Dev, Plot 79-80,Cherlapalli Phase 3 Ind Pk, Hyderabad 500039, India

[3] Jawaharlal Nehru Technol Univ, Dept Chem, CMR Engn Coll, Hyderabad 501401, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2019年 / 56卷 / 12期

关键词：

ONE-POT SYNTHESIS; EFFICIENT METHOD; INTRAMOLECULAR CYCLIZATION; OXIDATIVE AMINATION; C(SP(3))-H BONDS; DERIVATIVES; COPPER; PALLADIUM; BENZODIAZEPINE; INDOLES;

D O I：

10.1002/jhet.3722

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and efficient method for the synthesis of various aza-fused poly-hetero aromatics has been described. This protocol includes an intermolecular condensation followed by metal-free base-promoted intramolecular C?N coupling reaction. The advantage of this one-pot transformation lies in the use of simple cyclic amidines-like compounds without prefunctionalization of the starting heterocycles.

引用

收藏

页码：3267 / 3276

页数：10

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