SERS aptasensor from nanorod-nanoparticle junction for protein detection

被引：86
作者：
Wang, Yuling
Lee, Kyuwan
Irudayaraj, Joseph [1 ]
机构：
[1] Purdue Univ, Physiol Sensing Facil, Bindley Biosci Ctr, W Lafayette, IN 47907 USA
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 04期
关键词：
ENHANCED RAMAN-SCATTERING; THROMBIN DETECTION; SILVER ELECTRODE; GOLD NANORODS; DNA DETECTION; APTAMER; SPECTROSCOPY; PROBES; CANCER; IMMUNOASSAY;
D O I：
10.1039/b919607b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A multicomponent nanostructure comprising of gold nanorod-nanoparticle (AuNR-AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod-nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.
引用
收藏
页码：613 / 615
页数：3
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