Synthesis of thieno[3,4-d]pyrimidines by the reactions of 3-amino-4-carbamoylthiophene derivatives with 1,3-dicarbonyl compounds

被引：1

作者：

Ryndina, SA

Kadushkin, AV

Solov'eva, NP

Granik, VG

机构：

[1] State Sci Ctr Russian Federat, Organ Intermediate Prod & Dyes Inst, Moscow 103787, Russia

[2] All Russian Res Chem Pharmaceut Inst, Moscow 119815, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2002年 / 51卷 / 10期

关键词：

thiophenes; thieno[3,4-d]pyrimidines; 1,3-dicarbonyl compounds; cyclization; alkylation;

D O I：

10.1023/A:1021356603146

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reactions of ethyl 3-amino-4-carbamoyl-5-methylthiophene-2-carboxylate with 1,3-dicarbonyl compounds were studied. During the reactions, the corresponding ketone is eliminated to give ethyl 5-methyl-4-oxo-3,4-dihydrothieno[3,4-d]pyrimidine-7-carboxylates.

引用

页码：1879 / 1885

页数：7

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