Prevalence of obstructive sleep apnea in suicidal patients with major depressive disorder

被引：19

作者：

McCall, William, V ^{[1
]}

Benca, Ruth M. ^{[2
]}

Rumble, Meredith E. ^{[3
]}

Case, Doug ^{[4
]}

Rosenquist, Peter B. ^{[1
]}

Krystal, Andrew D. ^{[5
]}

机构：

[1] Georgia Augusta Univ, Dept Psychiat & Hlth Behav, Med Coll, Augusta, GA USA

[2] Univ Calif Irvine, Dept Psychiat & Human Behav, Irvine, CA 92717 USA

[3] Univ Wisconsin, Dept Psychiat, Madison, WI 53706 USA

[4] Wake Forest Sch Med, Dept Biostat & Data Sci, Div Publ Hlth Sci, Winston Salem, NC USA

[5] Univ Calif San Francisco, San Francisco, CA 94143 USA

来源：

JOURNAL OF PSYCHIATRIC RESEARCH | 2019年 / 116卷

关键词：

Major depressive disorder; Suicide; Treatment-resistance; Obstructive sleep apnea; POSITIVE AIRWAY PRESSURE; DAYTIME SLEEPINESS; CLINICAL-TRIAL; SYMPTOMS; CPAP; EPIDEMIOLOGY; INDIVIDUALS;

D O I：

10.1016/j.jpsychires.2019.06.015

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

In this paper, we report the rate of previously undiagnosed obstructive sleep apnea (OSA) in a randomized clinical trial (RCT) of suicidal patients with major depressive disorder (MDD). One hundred and twenty-five suicidal adults with MDD were recruited into a RCT. None were suspected to have OSA. Fourteen percent met diagnostic criteria for OSA. The Apnea Hypopnea Index (AHI) was predicted by increasing age, male sex, and higher Body Mass Index. However, neither the degree of daytime sleepiness nor the degree of insomnia predicted AHI severity. A high degree of suspicion is warranted for OSA in suicidal patients with MDD, and for patients with treatment-resistant depression.

引用

页码：147 / 150

页数：4

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