Sebaceous Carcinoma Epidemiology and Genetics: Emerging Concepts and Clinical Implications for Screening, Prevention, and Treatment

被引：32

作者：

Sargen, Michael R. ^{[1
]}

Starrett, Gabriel J. ^{[2
]}

Engels, Eric A. ^{[3
]}

Cahoon, Elizabeth K. ^{[4
]}

Tucker, Margaret A. ^{[5
]}

Goldstein, Alisa M. ^{[1
]}

机构：

[1] NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, Rockville, MD 20850 USA

[2] NCI, Lab Cellular Oncol, Ctr Canc Res, Bethesda, MD 20892 USA

[3] NCI, Infect & Immunoepidemiol Branch, Div Canc Epidemiol & Genet, Rockville, MD 20850 USA

[4] NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, Rockville, MD 20850 USA

[5] NCI, Human Genet Program, Div Canc Epidemiol & Genet, Rockville, MD 20850 USA

来源：

CLINICAL CANCER RESEARCH | 2021年 / 27卷 / 02期

关键词：

HUMAN-PAPILLOMAVIRUS TYPES; MERKEL CELL-CARCINOMA; CANCER-RISK; SURVIVAL; EXPRESSION; NEOPLASMS; PROTEIN; TUMORS; AIDS;

D O I：

10.1158/1078-0432.CCR-20-2473

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Sebaceous carcinoma is an aggressive skin cancer with a 5-year overall survival rate of 78% for localized/regional disease and 50% for metastatic disease. The incidence of this cancer has been increasing in the United States for several decades, but the underlying reasons for this increase are unclear. In this article, we review the epidemiology and genetics of sebaceous carcinoma, including recent population data and tumor genomic analyses that provide new insights into underlying tumor biology. We further discuss emerging evidence of a possible viral etiology for this cancer. Finally, we review the clinical implications of recent advances in sebaceous carcinoma research for screening, prevention, and treatment.

引用

页码：389 / 393

页数：5

共 51 条

[1] Cancer Screening Recommendations for Solid Organ Transplant Recipients: A Systematic Review of Clinical Practice Guidelines [J].

Acuna, S. A. ;

Huang, J. W. ;

Scott, A. L. ;

Micic, S. ;

Daly, C. ;

Brezden-Masley, C. ;

Kim, S. J. ;

Baxter, N. N. .

AMERICAN JOURNAL OF TRANSPLANTATION, 2017, 17 (01) :103-114

[2]

Blake PW, 2010, ARCH DERMATOL, V146, P625, DOI 10.1001/archdermatol.2010.105

[3] Sebaceous neoplasms and the immunoprofile of mismatch-repair proteins as a screening target for syndromic cases [J].

Boennelycke, Marie ;

Thomsen, Birthe M. ;

Holck, Susanne .

PATHOLOGY RESEARCH AND PRACTICE, 2015, 211 (01) :78-82

[4] Risk of Merkel Cell Carcinoma After Solid Organ Transplantation [J].

Clarke, Christina A. ;

Robbins, Hilary A. ;

Tatalovich, Zaria ;

Lynch, Charles F. ;

Pawlish, Karen S. ;

Finch, Jack L. ;

Hernandez, Brenda Y. ;

Fraumeni, Joseph F., Jr. ;

Madeleine, Margaret M. ;

Engels, Eric A. .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2015, 107 (02)

[5] Management of Perineural Invasion in Sebaceous Carcinoma of the Eyelid [J].

Connor, Michael ;

Droll, Lilly ;

Ivan, Doina ;

Cutlan, Jonathan ;

Weber, Randal S. ;

Frank, Steven J. ;

Esmaeli, Bita .

OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, 2011, 27 (05) :356-359

[6] Voriconazole and the Risk of Keratinocyte Carcinomas Among Lung Transplant Recipients in the United States [J].

D'Arcy, Monica E. ;

Pfeiffer, Ruth M. ;

Rivera, Donna R. ;

Hess, Gregory P. ;

Cahoon, Elizabeth K. ;

Arron, Sarah T. ;

Brownell, Isaac ;

Cowen, Edward W. ;

Israni, Ajay K. ;

Triplette, Matthew A. ;

Yanik, Elizabeth L. ;

Engels, Eric A. .

JAMA DERMATOLOGY, 2020, 156 (07) :772-779

[7]

DArcy ME, 2020, J NATL CANC I

[8] A Retrospective Review of 1349 Cases of Sebaceous Carcinoma [J].

Dasgupta, Tina ;

Wilson, Lynn D. ;

Yu, James B. .

CANCER, 2009, 115 (01) :158-165

[9] Merkel cell carcinoma and HIV infection [J].

Engels, EA ;

Frisch, M ;

Goedert, JJ ;

Biggar, RJ ;

Miller, RW .

LANCET, 2002, 359 (9305) :497-498

[10] Trends in cancer risk among people with AIDS in the United States 1980-2002 [J].

Engels, Eric A. ;

Pfeiffer, Ruth M. ;

Goedert, James J. ;

Virgo, Phillip ;

McNeel, Timothy S. ;

Scoppa, Steven M. ;

Biggar, Robert J. .

AIDS, 2006, 20 (12) :1645-1654

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