One-stage wound healing of fingertip injuries induced by treatment of artificial dermis

被引:10
作者
Lou, Xianghong [1 ]
Zhu, Haijun [1 ]
Xue, Hang [1 ]
Weng, Yuxiong [1 ]
Chen, Jianghai [1 ]
机构
[1] Wuhan Union Hosp Hand Surg, Jiefang Ave 1277, Wuhan 430022, Hubei, Peoples R China
基金
中国国家自然科学基金;
关键词
fingertip injury; artificial dermis; one-stage; wound healing; DIGIT TIP; MANAGEMENT; REGENERATION; RECONSTRUCTION; AMPUTATIONS;
D O I
10.1055/s-0044-102304
中图分类号
R61 [外科手术学];
学科分类号
摘要
Backround Fingertip injuries are common in both adults and children. Many operative and non-operative management techniques have been reported to restore the function and cosmetic shape of fingertips after injuries. Although these methods may be used for different indications in clinical settings, few of them can treat all kinds of fingertip injuries. In addition, there is controversy as to whether the surgical approach or the conservative approach is the optimal management for fingertip injuries. Methods Thirty-six fingers of 33 patients with fingertip injuries were included in the study. All wounds were treated with surgical debridement and artificial dermis coverage without further surgical treatment. Follow-up duration was 24.5 months on average. Results All injuries were categorised into four types - Allen's classification of fingertip injury type II, type III, type IV, and transverse amputations proximal to the lunula and close to the level of the distal interphalangeal (DIP) joint - and 28 of them had bone exposure. The defects of all fingers were restored in one stage within an average of 8 weeks. Although the length and width of the new fingertips were less than those of the contralateral fingertips, almost all patients were satisfied with the functional and cosmetic outcomes of their regenerated fingers. Conclusions One-stage wound healing of fingertip injuries induced by artificial dermis treatment is an easy and effective approach to restoring defects after injury with excellent functional and cosmetic results. Nearly all kinds of fingertip injuries can be managed with this method without any further surgical treatment. Therefore, this is a good alternative for the management of fingertip injuries.
引用
收藏
页码:269 / 275
页数:7
相关论文
共 18 条
[1]  
DOUGLAS BS, 1972, AUST PAEDIATR J, V8, P86
[2]   Fingertip and Thumb Tip Wounds: Changing Algorithms for Sensation, Aesthetics, and Function [J].
Germann, Guenter ;
Rudolf, Klaus D. ;
Levin, Scott L. ;
Hrabowski, Manuel .
JOURNAL OF HAND SURGERY-AMERICAN VOLUME, 2017, 42 (04) :274-285
[3]  
Hoigne D, 2013, J HAND SURG-BRIT EUR, P1
[4]   Dedifferentiated Schwann Cell Precursors Secreting Paracrine Factors Are Required for Regeneration of the Mammalian Digit Tip [J].
Johnston, Adam P. W. ;
Yuzwa, Scott A. ;
Carr, Matthew J. ;
Mahmud, Neemat ;
Storer, Mekayla A. ;
Krause, Matthew P. ;
Jones, Karen ;
Paul, Smitha ;
Kaplan, David R. ;
Miller, Freda D. .
CELL STEM CELL, 2016, 19 (04) :433-448
[5]  
Krauss Emily M, 2014, Hand (N Y), V9, P282, DOI 10.1007/s11552-014-9663-5
[6]   Fingertip Injuries: An Update on Management [J].
Lee, Donald H. ;
Mignemi, Megan E. ;
Crosby, Samuel N. .
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 2013, 21 (12) :756-766
[7]   SDF-1α/CXCR4 signaling mediates digit tip regeneration promoted by BMP-2 [J].
Lee, Jangwoo ;
Marrero, Luis ;
Yu, Ling ;
Dawson, Lindsay A. ;
Muneoka, Ken ;
Han, Manjong .
DEVELOPMENTAL BIOLOGY, 2013, 382 (01) :98-109
[8]  
Lynch KM, 2014, TISSUE ENG PT A, V20, P3122, DOI [10.1089/ten.tea.2014.0278, 10.1089/ten.TEA.2014.0278]
[9]   FINGERTIP INJURIES MANAGEMENT WITH SEMI-OCCLUSIVE DRESSING [J].
MENNEN, U ;
WIESE, A .
JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME, 1993, 18B (04) :416-422
[10]  
Miller Andrew J, 2015, Am J Orthop (Belle Mead NJ), V44, pE331