Use of lifesaving extracorporeal membrane oxygenation in a case of massive hydroxychloroquine overdose

Hydroxychloroquine (HCQ), approved by the Food and Drug Administration in 1955, has high potential for overdose due to its increasing use related to mortality and morbidity benefit in many autoimmune diseases. Lack in the current available data regarding standardized management and practical approach needed in overdose cases necessitates a discussion on this topic. The purpose of this case presentation is to add to the current medical literature on HCQ overdose and management, to determine possible guidelines for guiding therapy in future for HCQ toxicity, and to present recommendations for more efficient and timely management that may reduce the morbidity and mortality of patients with intentional or accidental HCQ overdose. The following core competencies are addressed in this article: Medical knowledge, Patient care, Interpersonal and communication skills, Practice-based learning and improvement