Mammary gland macrophages: Pleiotropic functions in mammary development

Mammary gland development is a complex process involving epithelial cells and supporting stromal cells. Macrophages (M circle divide s) are an important component of the mammary gland stroma and are critical for normal mammary gland development; however, the mechanisms by which macrophages regulate these processes are not well understood. M circle divide s are known to interact with numerous cell types, including epithelial cells, fibroblasts, adipocytes, and endothelial cells, all of which are significant components of mammary gland development. Therefore, the purpose of this review is to describe the interactions between M circle divide s and these various cell types and use this knowledge to identify potential functions of M circle divide s in the mammary gland.