The enigmatic parietal epithelial cell is finally getting noticed: a review

被引：58

作者：

Ohse, Takamoto ^{[1
]}

Pippin, Jeffrey W. ^{[1
]}

Chang, Alice M. ^{[1
]}

Krofft, Ronald D. ^{[1
]}

Miner, Jeffrey H. ^{[2
,3
]}

Vaughan, Michael R. ^{[1
]}

Shankland, Stuart J. ^{[1
]}

机构：

[1] Univ Washington, Div Nephrol, Dept Med, Seattle, WA 98195 USA

[2] Washington Univ, Sch Med, Dept Internal Med, Div Renal, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Cell Biol & Physiol, St Louis, MO 63110 USA

来源：

KIDNEY INTERNATIONAL | 2009年 / 76卷 / 12期

关键词：

albuminuria; glomerulus; parietal epithelial cells; podocytes; FOCAL SEGMENTAL GLOMERULOSCLEROSIS; TISSUE GROWTH-FACTOR; EXPERIMENTAL AUTOIMMUNE GLOMERULONEPHRITIS; GLOMERULAR CRESCENT FORMATION; INTRINSIC RENAL-CELLS; ADULT HUMAN KIDNEY; BASEMENT-MEMBRANE; DIFFERENTIAL EXPRESSION; RAT-KIDNEY; COLLAPSING GLOMERULOPATHY;

D O I：

10.1038/ki.2009.386

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Although the normal glomerulus comprises four resident cell types, least is known about the parietal epithelial cells (PECs). This comprehensive review addresses the cellular origin of PECs, discusses the normal structure and protein makeup of PECs, describes PEC function, and defines the responses to injury in disease and how these events lead to clinical events. The data show that PECs have unique properties and that new functions are being recognized such as their role in differentiating into podocytes during disease. Kidney International (2009) 76, 1225-1238; doi:10.1038/ki.2009.386; published online 21 October 2009

引用

页码：1225 / 1238

页数：14

共 120 条

[1] Parietal epithelia cells in the urine as a marker of disease activity in glomerular diseases [J].

Achenbach, Johannes ;

Mengel, Michael ;

Tossidou, Irini ;

Peters, Imke ;

Park, Joon-Keun ;

Haubitz, Marion ;

Ehrich, Jochen H. ;

Haller, Hermann ;

Schiffer, Mario .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2008, 23 (10) :3138-3145

[2] Isolation, culture, and characterization of endothelial cells from mouse glomeruli [J].

Akis, N ;

Madaio, MP .

KIDNEY INTERNATIONAL, 2004, 65 (06) :2223-2227

[3]

ALCORN D, 1993, KIDNEY INT, V44, pS35

[4] PDGF-RECEPTOR LOCALIZES TO MESANGIAL, PARIETAL EPITHELIAL, AND INTERSTITIAL-CELLS IN HUMAN AND PRIMATE KIDNEYS [J].

ALPERS, CE ;

SEIFERT, RA ;

HUDKINS, KL ;

JOHNSON, RJ ;

BOWENPOPE, DF .

KIDNEY INTERNATIONAL, 1993, 43 (02) :286-294

[5] Recruitment of Podocytes from Glomerular Parietal Epithelial Cells [J].

Appel, Daniel ;

Kershaw, David B. ;

Smeets, Bart ;

Yuan, Gang ;

Fuss, Astrid ;

Frye, Bjoern ;

Elger, Marlies ;

Kriz, Wilhelm ;

Floege, Juergen ;

Moeller, Marcus J. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 20 (02) :333-343

[6]

Arakawa M, 1977, Contrib Nephrol, V6, P73

[7] Potassium conductances and proliferation in conditionally immortalized renal glomerular mesangial cells from the H-2K(b)-tsA58 transgenic mouse [J].

Barber, RD ;

Woolf, AS ;

Henderson, RM .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1997, 1355 (02) :191-203

[8] Glomerular epithelial-mesenchymal transdifferentiation in pauci-immune crescentic glomerulonephritis [J].

Bariety, J ;

Hill, GS ;

Mandet, C ;

Irinopoulou, T ;

Jacquot, C ;

Meyrier, A ;

Bruneval, P .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2003, 18 (09) :1777-1784

[9] Parietal podocytes in normal human glomeruli [J].

Bariety, Jean ;

Mandet, Chantal ;

Hill, Gary S. ;

Bruneval, Patrick .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 17 (10) :2770-2780

[10] The kd/kd mouse is a model of collapsing Glomerulopathy [J].

Barisoni, L ;

Madaio, MP ;

Eraso, M ;

Gasser, DL ;

Nelson, PJ .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2005, 16 (10) :2847-2851

← 1 2 3 4 5 6 7 8 9 10 →