Snap: an integrated SNP annotation platform

被引：36

作者：

Li, Shengting

Ma, Lijia

Li, Heng

Vang, Soren

Hu, Yafeng

Bolund, Lars

Wang, Jun ^{[1
]}

机构：

[1] Univ Aarhus, Inst Human Genet, DK-8000 Aarhus C, Denmark

[2] Chinese Acad Sci, BGI, Beijing 101300, Peoples R China

[3] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China

[4] Aarhus Univ Hosp, Res Unit Mol Med, DK-8200 Aarhus N, Denmark

[5] Fac Hlth Sci, DK-8200 Aarhus N, Denmark

[6] Peking Univ, Coll Life Sci, Beijing 100871, Peoples R China

来源：

NUCLEIC ACIDS RESEARCH | 2007年 / 35卷

基金：

中国国家自然科学基金;

关键词：

EXONIC SPLICING ENHANCERS; DATABASE; IDENTIFICATION; INFORMATION; RESOURCE; UPDATE; GENOME; TOOLS;

D O I：

10.1093/nar/gkl969

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Snap (Single Nucleotide Polymorphism Annotation Platform) is a server designed to comprehensively analyze single genes and relationships between genes basing on SNPs in the human genome. The aim of the platform is to facilitate the study of SNP finding and analysis within the framework of medical research. Using a user-friendly web interface, genes can be searched by name, description, position, SNP ID or clone name. Several public databases are integrated, including gene information from Ensembl, protein features from Uniprot/SWISS-PROT, Pfam and DAS-CBS. Gene relationships are fetched from BIND, MINT, KEGG and are integrated with ortholog data from TreeFam to extend the current interaction networks. Integrated tools for primer-design and mis-splicing analysis have been developed to facilitate experimental analysis of individual genes with focus on their variation. Snap is available at http://snap.humgen.au.dk/ and at http://snap.genomics.org.cn/.

引用

页码：D707 / D710

页数：4

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