Natural Phenolic Compounds From Medicinal Herbs and Dietary Plants: Potential Use for Cancer Prevention

被引:661
作者
Huang, Wu-Yang [1 ]
Cai, Yi-Zhong [1 ]
Zhang, Yanbo [2 ]
机构
[1] Univ Hong Kong, Sch Biol Sci, Hong Kong, Hong Kong, Peoples R China
[2] Univ Hong Kong, Sch Chinese Med, Hong Kong, Hong Kong, Peoples R China
来源
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL | 2010年 / 62卷 / 01期
关键词
CELL-CYCLE ARREST; ANTIOXIDANT-RESPONSE ELEMENT; RADICAL SCAVENGING ACTIVITY; MILL WASTE-WATER; IN-VITRO; ANTIBACTERIAL ACTIVITY; HETEROCYCLIC AMINES; MOLECULAR TARGETS; CHLOROGENIC ACID; ENDOPHYTIC FUNGI;
D O I
10.1080/01635580903191585
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Natural phenolic compounds play an important role in cancer prevention and treatment. Phenolic compounds from medicinal herbs and dietary plants include phenolic acids, flavonoids, tannins, stilbenes, curcuminoids, coumarins, lignans, quinones, and others. Various bioactivities of phenolic compounds are responsible for their chemopreventive properties (e.g., antioxidant, anticarcinogenic, or antimutagenic and anti-inflammatory effects) and also contribute to their inducing apoptosis by arresting cell cycle, regulating carcinogen metabolism and ontogenesis expression, inhibiting DNA binding and cell adhesion, migration, proliferation or differentiation, and blocking signaling pathways. This review covers the most recent literature to summarize structural categories and molecular anticancer mechanisms of phenolic compounds from medicinal herbs and dietary plants.
引用
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页码:1 / 20
页数:20
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