Transcriptional regulation of strigolactone signalling in Arabidopsis

被引：295

作者：

Wang, Lei ^{[1
,2
]}

Wang, Bing ^{[1
,2
]}

Yu, Hong ^{[1
,2
]}

Guo, Hongyan ^{[1
,2
]}

Lin, Tao ^{[1
,2
]}

Kou, Liquan ^{[1
,2
]}

Wang, Anqi ^{[1
,2
,4
]}

Shao, Ning ^{[1
,2
]}

Ma, Haiyan ^{[1
,2
]}

Xiong, Guosheng ^{[3
,5
]}

Li, Xiaoqiang ^{[6
]}

Yang, Jun ^{[6
]}

Chu, Jinfang ^{[1
,2
,4
]}

Li, Jiayang ^{[1
,2
,4
]}

机构：

[1] Chinese Acad Sci, Innovat Acad Seed Design, Inst Genet & Dev Biol, State Key Lab Plant Genom, Beijing, Peoples R China

[2] Chinese Acad Sci, Innovat Acad Seed Design, Inst Genet & Dev Biol, Natl Ctr Plant Gene Res Beijing, Beijing, Peoples R China

[3] Chinese Acad Agr Sci, Guangdong Lab Lingnan Modern Agr, Genome Anal Lab, Minist Agr,Agr Genom Inst Shenzhen, Shenzhen, Peoples R China

[4] Univ Chinese Acad Sci, Beijing, Peoples R China

[5] Nanjing Agr Univ, Plant Phen Res Ctr, Nanjing, Peoples R China

[6] Chinese Acad Sci, Shanghai Inst Organ Chem, CAS Key Lab Energy Regulat, Shanghai, Peoples R China

来源：

NATURE | 2020年 / 583卷 / 7815期

基金：

中国国家自然科学基金;

关键词：

SHOOT DEVELOPMENT; RESPONSES; INHIBITION; EXPRESSION; KARRIKINS; SEQUENCE; RECEPTOR; DOWNSTREAM; PROTEINS; COMPLEX;

D O I：

10.1038/s41586-020-2382-x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Plant hormones known as strigolactones control plant development and interactions between host plants and symbiotic fungi or parasitic weeds(1-4). In Arabidopsis thaliana and rice, the proteins DWARF14 (D14), MORE AXILLARY GROWTH 2 (MAX2), SUPPRESSOR OF MAX2-LIKE 6, 7 and 8 (SMXL6, SMXL7 and SMXL8) and their orthologues form a complex upon strigolactone perception and play a central part in strigolactone signalling(5-10). However, whether and how strigolactones activate downstream transcription remains largely unknown. Here we use a synthetic strigolactone to identify 401 strigolactone-responsive genes in Arabidopsis, and show that these plant hormones regulate shoot branching, leaf shape and anthocyanin accumulation mainly through transcriptional activation of the BRANCHED 1, TCP DOMAIN PROTEIN 1 and PRODUCTION OF ANTHOCYANIN PIGMENT 1 genes. We find that SMXL6 targets 729 genes in the Arabidopsis genome and represses the transcription of SMXL6, SMXL7 and SMXL8 by binding directly to their promoters, showing that SMXL6 serves as an autoregulated transcription factor to maintain the homeostasis of strigolactone signalling. These findings reveal an unanticipated mechanism through which a transcriptional repressor of hormone signalling can directly recognize DNA and regulate transcription in higher plants.

引用

页码：277 / +

页数：22

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