New products from alkali fusion of ginkgolides A and B

被引：10

作者：

Hu, LH

Chen, ZL ^{[1
]}

Xie, YY

Jiang, YY

Zhen, HW

机构：

[1] Acad Sinica, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China

[2] Second Mil Med Univ, Shanghai 200433, Peoples R China

[3] Navy 411 Hosp, Shanghai 200081, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2000年 / 2卷 / 02期

关键词：

ginkgolide analogs; structure and activity relationship;

D O I：

10.1080/10286020008039899

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Alkali fusion of ginkgolides A and B has afforded five unexpected products 3-7. Their structures were established from their spectral data and chemical reactions. They were evaluated for their in vitro activity to inhibit the platelet-activating factor-induced aggregation of rabbit platelets and show less potency than ginkgolides A and B.

引用

页码：103 / 110

页数：8

共 5 条

[1] AGGREGATION OF BLOOD PLATELETS BY ADENOSINE DIPHOSPHATE AND ITS REVERSAL [J].