Distribution of tetrodotoxin in the body of the blue-ringed octopus (Hapalochlaena maculosa)

被引：46
作者：
Yotsu-Yamashita, Mari
Mebs, Dietrich
Flachsenberger, Wolfgang
机构：
[1] Goethe Univ Frankfurt, Zentrum Rechtsmed, D-60596 Frankfurt, Germany
[2] Tohoku Univ, Grad Sch Agr Sci, Aoba Ku, Sendai, Miyagi 9818555, Japan
来源：
TOXICON | 2007年 / 49卷 / 03期
关键词：
tetrodotoxin; blue-ringed octopus; Hapalochlaena maculosa; posterior salivary gland;
D O I：
10.1016/j.toxicon.2006.10.008
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Tetrodotoxin (TTX) was quantitatively assayed in six specimens of semi-adult blue-ringed octopus, Hapalochlaena maculosa, by a post-column fluorescent-HPLC system. TTX was found to be present in all body parts, e.g. in high concentrations in the arms followed by the abdomen and cephalothorax. The toxin is not associated exclusively with the posterior salivary gland. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：410 / 412
页数：3
相关论文
共 12 条
[1]   Simple fold composition and modular architecture of the nuclear pore complex [J].
Devos, D ;
Dokudovskaya, S ;
Williams, R ;
Alber, F ;
Eswar, N ;
Chait, BT ;
Rout, MP ;
Sali, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (07) :2172-2177
[2]   LACK OF EFFECT OF TETRODOTOXIN AND OF AN EXTRACT FROM THE POSTERIOR SALIVARY-GLAND OF THE BLUE-RINGED OCTOPUS FOLLOWING INJECTION INTO THE OCTOPUS AND FOLLOWING APPLICATION TO ITS BRACHIAL NERVE [J].
FLACHSENBERGER, W ;
KERR, DIB .
TOXICON, 1985, 23 (06) :997-999
[3]  
Flecker H, 1955, MED J AUSTRALIA, V2, P329
[4]  
GIBBS PJ, 1977, TOXICON, V16, P59
[5]   TETRODOTOXIN-PRODUCING BACTERIA FROM THE BLUE-RINGED OCTOPUS OCTOPUS-MACULOSUS [J].
HWANG, DF ;
ARAKAWA, O ;
SAITO, T ;
NOGUCHI, T ;
SIMIDU, U ;
TSUKAMOTO, K ;
SHIDA, Y ;
HASHIMOTO, K .
MARINE BIOLOGY, 1989, 100 (03) :327-332
[6]   VIBRIO-ALGINOLYTICUS, A TETRODOTOXIN-PRODUCING BACTERIUM, IN THE INTESTINES OF THE FISH FUGU-VERMICULARIS-VERMICULARIS [J].
NOGUCHI, T ;
HWANG, DF ;
ARAKAWA, O ;
SUGITA, H ;
DEGUCHI, Y ;
SHIDA, Y ;
HASHIMOTO, K .
MARINE BIOLOGY, 1987, 94 (04) :625-630
[7]   MACULOTOXIN - NEUROTOXIN FROM VENOM GLANDS OF OCTOPUS HAPALOCHLAENA-MACULOSA IDENTIFIED AS TETRODOTOXIN [J].
SHEUMACK, DD ;
HOWDEN, MEH ;
SPENCE, I ;
QUINN, RJ .
SCIENCE, 1978, 199 (4325) :188-189
[8]   Electrospray ionization mass spectrometry of tetrodotoxin and its analogs: Liquid chromatography/mass spectrometry, tandem mass spectrometry, and liquid chromatography/tandem mass spectrometry [J].
Shoji, Y ;
Yotsu-Yamashita, M ;
Miyazawa, T ;
Yasumoto, T .
ANALYTICAL BIOCHEMISTRY, 2001, 290 (01) :10-17
[9]  
Sutherland S., 2001, Australian animal toxins: the creatures, their toxins, and care of the poisoned patient
[10]   TOXINS AND MODE OF ENVENOMATION OF COMMON RINGED OR BLUE-BANDED OCTOPUS [J].
SUTHERLAND, SK ;
LANE, WR .
MEDICAL JOURNAL OF AUSTRALIA, 1969, 1 (18) :893-+
12