Ghost cell odontogenic carcinoma arising in calcifying odontogenic cyst

被引:20
作者
Motosugi, Utaroh [1 ]
Ogawa, Ikuko [2 ]
Yoda, Tetsuya [3 ]
Abe, Takahlro [3 ,4 ]
Sugasawa, Masashi [4 ]
Murata, Shin-ichi [1 ]
Yasuda, Masanorl [1 ]
Sakurai, Takaki [1 ]
Shimizu, Yoshihiko [1 ]
Shimizu, Michio [1 ]
机构
[1] Saitama Med Univ, Int Med Ctr, Dept Pathol, Saitama 3501298, Japan
[2] Hiroshima Univ, Hiroshima Univ Hosp, Ctr Oral Clin Examinat, Hiroshima 7348551, Japan
[3] Saitama Med Univ, Dept Oral & Maxillofacial Surg, Saitama 3501495, Japan
[4] Saitama Med Univ, Int Med Ctr, Dept Head & Neck Surg, Saitama 3501298, Japan
关键词
Ghost cell odontogenic carcinoma; Calcifying odontogenic cyst; OF-THE-LITERATURE; TUMOR; MAXILLA;
D O I
10.1016/j.anndiagpath.2009.02.008
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
A case of exceptionally rare odontogenic malignant tumor. called ghost cell odontogenic carcinoma, is described. The tumor was considered to be derived from calcifying odontogenic cyst, which had been resected 5 years before. In the present resected specimen, cellular atypia, mitotic activity, Ki-67 labeling index, and p53 positivity were all increased in comparison with the initially resected specimen. This is a valuable case in which malignant transformation from calcifying odontogenic cyst to ghost cell odontogenic carcinoma was proven by the histopathologic and immunohistochemical findings. Pathologists should be aware of this rare entity. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:394 / 397
页数:4
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