Ghost cell odontogenic carcinoma arising in calcifying odontogenic cyst

被引:20
作者
Motosugi, Utaroh [1 ]
Ogawa, Ikuko [2 ]
Yoda, Tetsuya [3 ]
Abe, Takahlro [3 ,4 ]
Sugasawa, Masashi [4 ]
Murata, Shin-ichi [1 ]
Yasuda, Masanorl [1 ]
Sakurai, Takaki [1 ]
Shimizu, Yoshihiko [1 ]
Shimizu, Michio [1 ]
机构
[1] Saitama Med Univ, Int Med Ctr, Dept Pathol, Saitama 3501298, Japan
[2] Hiroshima Univ, Hiroshima Univ Hosp, Ctr Oral Clin Examinat, Hiroshima 7348551, Japan
[3] Saitama Med Univ, Dept Oral & Maxillofacial Surg, Saitama 3501495, Japan
[4] Saitama Med Univ, Int Med Ctr, Dept Head & Neck Surg, Saitama 3501298, Japan
关键词
Ghost cell odontogenic carcinoma; Calcifying odontogenic cyst; OF-THE-LITERATURE; TUMOR; MAXILLA;
D O I
10.1016/j.anndiagpath.2009.02.008
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
A case of exceptionally rare odontogenic malignant tumor. called ghost cell odontogenic carcinoma, is described. The tumor was considered to be derived from calcifying odontogenic cyst, which had been resected 5 years before. In the present resected specimen, cellular atypia, mitotic activity, Ki-67 labeling index, and p53 positivity were all increased in comparison with the initially resected specimen. This is a valuable case in which malignant transformation from calcifying odontogenic cyst to ghost cell odontogenic carcinoma was proven by the histopathologic and immunohistochemical findings. Pathologists should be aware of this rare entity. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:394 / 397
页数:4
相关论文
共 50 条
[21]   Radiographic analysis of a calcifying odontogenic cyst [J].
Hu Wang ;
Guang-ning Zheng ;
Bo Han ;
Hong-bing Wu ;
Xun-guang Lei .
Oral Radiology, 2001, 17 (1) :61-64
[22]   Recurrent hybrid odontogenic tumor of calcifying odontogenic cyst and ameloblastic fibroma [J].
Yeh, Tzu Hsien ;
Chen, Yen-Chang ;
Lee, Yi-Pang ;
Chiang, Chun-Pin .
JOURNAL OF DENTAL SCIENCES, 2023, 18 (02) :933-935
[23]   PATHOGENESIS OF THE CALCIFYING ODONTOGENIC CYST (GORLIN-CYST) [J].
DONATH, K ;
KLEINHANS, V ;
GUNDLACH, KKH .
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1979, 384 (03) :307-324
[24]   A hybrid odontogenic tumor of calcifying odontogenic cyst, ameloblastic fibroma, and complex odontoma [J].
Chen, Yen-Chang ;
Chen, Peir-Rong ;
Lee, Yi-Pang ;
Chiang, Chun-Pin .
JOURNAL OF DENTAL SCIENCES, 2022, 17 (01) :595-597
[25]   Bilateral Calcifying Odontogenic Cyst: A Rare Entity [J].
Gadipelly S. ;
Reddy V.B. ;
Sudheer M. ;
Kumar N.V. ;
Harsha G. .
Journal of Maxillofacial and Oral Surgery, 2015, 14 (3) :826-831
[26]   Cystic Odontogenic Tumor with Features of Calcifying Odontogenic Cyst in 3 Cats and a Dog [J].
Babbitt, Samuel G. ;
Bell, Cynthia M. ;
Raleigh, Matthew ;
Haggerty, Kevin ;
Feigin, Kristina .
JOURNAL OF VETERINARY DENTISTRY, 2022, 39 (02) :194-202
[27]   Histopathological study of a characteristic calcifying odontogenic cyst [J].
Hwang, Ming-Jay ;
Lang, Ming-Jane ;
Jin, Ying-Tai ;
Chiang, Chun-Pin .
JOURNAL OF DENTAL SCIENCES, 2022, 17 (01) :578-579
[28]   Calcifying Odontogenic Cyst Presenting Odontogenic Keratocyst-Like Areas: A Rare Case Report [J].
Bezerra, Helen Kaline Farias ;
de Moraes Ramos-Perez, Flavia Maria ;
dos Anjos Pontual, Andrea ;
Gueiros, Luiz Alcino Monteiro ;
de Almeida, Oslei Paes ;
Vargas, Pablo Agustin ;
da Cruz Perez, Danyel Elias .
HEAD & NECK PATHOLOGY, 2024, 18 (01)
[29]   An Intricate Clinicopathologic Presentation of Calcifying Odontogenic Cyst [J].
Ghosh, Arup K. ;
Kabiraj, Arpita ;
Khaitan, Tanya ;
Bhattacharya, Preeti Tomar ;
Pal, Debarghya .
ORAL & MAXILLOFACIAL PATHOLOGY JOURNAL, 2015, 6 (02) :646-649
[30]   Proliferative activity and subtyping of calcifying odontogenic cyst [J].
Toida, M .
PATHOLOGY INTERNATIONAL, 2000, 50 (01) :81-83