Hyperthermic intrathoracic chemotherapy combined to iterative cytoreductive surgery to treat a pleural carcinosis from psudomixoma peritonei. A case report

被引：1
|
作者：
Lococo, F. [1 ]
Di Giorgio, A. [2 ]
Iaffaldano, A. [1 ]
Schinzari, G. [3 ]
Tabacco, D. [1 ]
Aceto, P. [4 ]
Abatini, C. [2 ]
Sollazzi, L. [4 ]
Margaritora, S. [1 ]
机构：
[1] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli, Unit Thorac Surg, IRCCS, Rome, Italy
[2] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli, IRCCS, Gen Surg, Rome, Italy
[3] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli, Oncol Unit, IRCCS, Rome, Italy
[4] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli, Anaesthesiol Unit, IRCCS, Rome, Italy
来源：
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | 2021年 / 25卷 / 01期
关键词：
Chemotherapy; Hyperthermic; Psedomixoma; Intrathoracic chemotherapy; PSEUDOMYXOMA PERITONEI;
D O I：
10.26355/eurrev_202101_24403
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Pseudomyxoma peritonei (PMP) is an uncommon disease with locally-invasive attitude. Intrathoracic spread is rarely reported and its management extremely challenging. A 51-year-old Caucasian female presented with left pleural carcinosis 9-months after two sequential abdominal surgical procedures combined with HIPEC for low-grade PMP. Cytoreductive surgery (pleurectomy/decortication) was followed by 60-minutes hyperthermic intrathoracic chemotherapy mitomycin-C (215 mg/m2) infusing at same temperature (42 degrees C) and intrapleural pression (2-4 mm(H)20). No intra-operative complication occurred, the post-op stay was uneventful and no sign of recurrence was observed 9-months after surgery. Cytoreductive thoracic surgery and hyperthermic chemotherapy (HITHOC) could be a feasible therapeutic option in very selected cases.
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收藏
页码：362 / 365
页数：4
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