Visual evoked potentials changes with surgery in primary congenital glaucoma: a pilot study

被引:1
作者
ElBahwash, Mai AbdelNabi Mohamed [1 ]
Morsy, Mahmoud Hassan [1 ]
Hegazy, Amira Saad Mahmoud [2 ]
Bayoumi, Nader Hussein Lotfy [1 ]
机构
[1] Alexandria Univ, Fac Med, Ophthalmol Dept, 311 Horeya Ave, Alexandria, Egypt
[2] Damanhour Eye Hosp, Damanhour, Egypt
关键词
Primary congenital glaucoma; Visual evoked potentials; Optic nerve; Intraocular pressure; Electrophysiology;
D O I
10.1007/s10792-021-01753-w
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Objective To report the flash visual evoked potential (VEP) findings in children with primary congenital glaucoma (PCG) before and after successful surgical control of the intraocular pressure (IOP). Methods The study enrolled children presenting with PCG to the Ophthalmology Department of Alexandria Main University Hospital in the period between June and December 2019. All study participants were subjected to a standard protocol of examination, to confirm the diagnosis of PCG. The child was then referred for flash VEP testing. Peaks were designated as negative and positive waves in a numerical sequence (N1, P1, N2, P2, N3 and P3). The child was then scheduled for surgery within 1 week of presentation. Postoperative VEP testing was scheduled as soon as feasible and was conducted in the same way as the preoperative VEP testing. Results The study was conducted on 11 (four right) eyes of eight (five males) children. The mean +/- standard deviation of the age of the study children at presentation and at postoperative VEP testing was 3.5 +/- 1.6 and 5.1 +/- 3.0 months, respectively. The study eyes mean +/- standard deviation IOP at presentation and at postoperative VEP testing was 23.0 +/- 6.7 and 8.3 +/- 2.4 mmHg, respectively (p < 0.0001). There were a statistically insignificant reduction in P2 implicit time (p = 0.235) and a statistically insignificant increase in each of N1-P1 (p = 0.15) and N2-P2 (p = 0.67) amplitudes postoperatively than preoperatively. Conclusions IOP elevation in PCG adversely affects the optic nerve function, but, at least in the short term, has no permanent detrimental effect on the optic nerve function as evidenced by the improvement in the VEP parameters.
引用
收藏
页码:1981 / 1988
页数:8
相关论文
共 16 条
  • [1] Primary and Secondary Congenital Glaucoma: Baseline Features From a Registry at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia
    Alanazi, Farhan F.
    Song, Jonathan C.
    Mousa, Ahmed
    Morales, Jose
    Al Shahwan, Sami
    Alodhayb, Sami
    Al Jadaan, Ibrahim
    Al-Turkmani, Shahira
    Edward, Deepak P.
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 2013, 155 (05) : 882 - 889
  • [2] [Anonymous], VISUALLY EVOKED POTE
  • [3] Bayoumi NL., 2016, J EGYPT OPHTHALMOL, V109, P85, DOI DOI 10.4103/2090-0686.193398
  • [4] Bean, 2019, J VIS EXP, V2019
  • [5] Bhade A V, 1987, Indian J Ophthalmol, V35, P265
  • [6] FILCHIKOVA LI, 1992, VESTN OFTALMOL, V108, P15
  • [7] A retrospective survey of childhood glaucoma prevalence according to Childhood Glaucoma Research Network classification
    Hoguet, Ambika
    Grajewski, Alana
    Hodapp, Elizabeth
    Chang, Ta Chen Peter
    [J]. INDIAN JOURNAL OF OPHTHALMOLOGY, 2016, 64 (02) : 118 - 123
  • [8] Combined trabeculotomy-trabeculectomy using the modified Safer Surgery System augmented with MMC: its long-term outcomes of glaucoma treatment in Asian children
    Hsu, Cherng-Ru
    Chen, Yi-Hao
    Tai, Ming-Cheng
    Lu, Da-Wen
    [J]. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2018, 256 (06) : 1187 - 1194
  • [9] Kaushik S, 2018, CLIN EXPT VISION EYE, V1
  • [10] Childhood blindness at a school for the blind in Riyadh, Saudi Arabia
    Kotb, AA
    Hammouda, EF
    Tabbara, KF
    [J]. OPHTHALMIC EPIDEMIOLOGY, 2006, 13 (01) : 1 - 5