Interference by antifolate drugs in a folate competitive protein-binding assay

被引：1

作者：

Hardcastle, A ^{[1
]}

Clarke, S ^{[1
]}

Aherne, W ^{[1
]}

机构：

[1] INST CANC RES,CRC,CTR CANC THERAPEUT,SUTTON SM2 5NG,SURREY,ENGLAND

来源：

CANCER CHEMOTHERAPY AND PHARMACOLOGY | 1997年 / 39卷 / 06期

关键词：

antifolate drugs; protein-binding assay;

D O I：

10.1007/s002800050613

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：552 / 553

页数：2

共 12 条

[1]

BEARDSLEY GP, 1989, J BIOL CHEM, V264, P328

[2] Phase I trial of ZDI694, a new folate-based thymidylate synthase inhibitor, in patients with solid tumors [J].

Clarke, SJ ;

Hanwell, J ;

deBeer, M ;

Planting, A ;

VerweiJ, J ;

Walker, M ;

Smith, R ;

Jackman, AL ;

Hughes, LR ;

Harrap, KR ;

Kennealey, GT ;

Judson, IR .

JOURNAL OF CLINICAL ONCOLOGY, 1996, 14 (05) :1495-1503

[3] 'Tomudex' (ZD1694): Results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia [J].

Cunningham, D ;

Zalcberg, JR ;

Rath, U ;

Olver, I ;

VanCutsem, E ;

Svensson, C ;

Seitz, JF ;

Harper, P ;

Kerr, D ;

PerezManga, G ;

Azab, M ;

Seymour, L ;

Lowery, K ;

Ackland, SP ;

Basser, RL ;

Clarke, SJ ;

Goldstein, D ;

Green, MD ;

Grygiel, JJ ;

McKendrick, JJ ;

Millward, MJ ;

Olver, IN ;

Tattersall, MHN ;

Thomson, DB ;

Jakesz, R ;

Buset, M ;

Tueni, EA ;

VanCutsem, EJD ;

Bauer, J ;

Beska, F ;

Adenis, A ;

Brunet, R ;

Francois, E ;

Paillot, B ;

Rougier, P ;

Fink, UFW ;

Knuth, KRA ;

Koenig, HJ ;

Bohme, MWJ ;

Wander, HE ;

Amadori, D ;

Frassineti, L ;

Cocconi, G ;

Passalacqua, R ;

Frigerio, F ;

Barni, S ;

Luporini, G ;

Labianca, R ;

Marini, G ;

Zaniboni, A .

EUROPEAN JOURNAL OF CANCER, 1995, 31A (12) :1945-1954

[4]

DUCH DS, 1993, CANCER RES, V53, P810

[5] Folate-based thymidylate synthase inhibitors as anticancer drugs [J].

Jackman, AL ;

Calvert, AH .

ANNALS OF ONCOLOGY, 1995, 6 (09) :871-881

[6] ZD1694 (TOMUDEX) - A NEW THYMIDYLATE SYNTHASE INHIBITOR WITH ACTIVITY IN COLORECTAL-CANCER [J].

JACKMAN, AL ;

FARRUGIA, DC ;

GIBSON, W ;

KIMBELL, R ;

HARRAP, KR ;

STEPHENS, TC ;

AZAB, M ;

BOYLE, FT .

EUROPEAN JOURNAL OF CANCER, 1995, 31A (7-8) :1277-1282

[7]

JACKMAN AL, 1995, PURINE PYRIMIDINE ME, V8, P185

[8]

JUDSON IR, 1996, ANN ONCOL S1, V7, P88

[9] EVALUATION OF A RADIOASSAY FOR SERUM FOLATE AND EFFECTS OF ASCORBATE AND METHOTREXATE [J].

LINDEMANS, J ;

VANKAPEL, J ;

ABELS, J .

CLINICA CHIMICA ACTA, 1975, 65 (01) :15-20

[10]

Rafi I, 1995, CLIN CANCER RES, V1, P1275

← 1 2 →