Derivatized cyclodextrins as peptidomimetics: Influence on neurite growth

被引：11

作者：

Borrajo, AMP

Gorin, BI

Dostaler, SM

Riopelle, RJ

Thatcher, GRJ

机构：

[1] QUEENS UNIV,DEPT CHEM,KINGSTON,ON K7L 3N6,CANADA

[2] QUEENS UNIV,DEPT MED NEUROL,KINGSTON,ON K7L 3N6,CANADA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 09期

关键词：

D O I：

10.1016/S0960-894X(97)00180-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Per-6-bromo-6-deoxy-cyclodextrins may be functionalized to yield amine-derivatized cyclodextrin mimics of glycosaminoglycan sulfate binding domains of peptides, which inhibit neurite growth in vitro. (C) 1997 Elsevier Science Ltd.

引用

页码：1185 / 1190

页数：6

共 22 条

[1] PER-3,6-ANHYDRO-ALPHA-CYCLODEXTRIN AND PER-3,6-ANHYDRO-BETA-CYCLODEXTRIN [J].

ASHTON, PR ;

ELLWOOD, P ;

STATON, I ;

STODDART, JF .

JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (26) :7274-7280

[2] Amino acid derivatives of beta-cyclodextrin [J].

Ashton, PR ;

Koniger, R ;

Stoddart, JF ;

Alker, D ;

Harding, VD .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (03) :903-908

[3] IMPROVED ACYLATION RATES WITHIN CYCLODEXTRIN COMPLEXES FROM FLEXIBLE CAPPING OF THE CYCLODEXTRIN AND FROM ADJUSTMENT OF THE SUBSTRATE GEOMETRY [J].

BRESLOW, R ;

CZARNIECKI, MF ;

EMERT, J ;

HAMAGUCHI, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (02) :762-770

[4] DETERMINATION OF THE NUMBER OF ENDOTHELIAL-CELLS IN CULTURE USING AN ACID-PHOSPHATASE ASSAY [J].

CONNOLLY, DT ;

KNIGHT, MB ;

HARAKAS, NK ;

WITTWER, AJ ;

FEDER, J .

ANALYTICAL BIOCHEMISTRY, 1986, 152 (01) :136-140

[5] MOLECULAR CORRELATES OF SPINAL-CORD REPAIR IN THE EMBRYONIC CHICK - HEPARAN-SULFATE AND CHONDROITIN SULFATE PROTEOGLYCANS [J].

DOW, KE ;

ETHELL, DW ;

STEEVES, JD ;

RIOPELLE, RJ .

EXPERIMENTAL NEUROLOGY, 1994, 128 (02) :233-238

[6] SUPRAMOLECULAR CHEMISTRY .46. MOLECULAR RECOGNITION OF NUCLEOTIDES, NUCLEOSIDES, AND SUGARS BY AMINOCYCLODEXTRINS [J].

ELISEEV, AV ;

SCHNEIDER, HJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (14) :6081-6088

[7] CONTROL OF ANGIOGENESIS WITH SYNTHETIC HEPARIN SUBSTITUTES [J].

FOLKMAN, J ;

WEISZ, PB ;

JOULLIE, MM ;

LI, WW ;

EWING, WR .

SCIENCE, 1989, 243 (4897) :1490-1493

[8]

FUJEDI P, 1989, CARBOHYD RES, V192, P366

[9]

GORIN BI, 1996, TETRAHEDRON LETT, P4647

[10] THE SYNTHESIS OF FUNCTIONALIZED CYCLODEXTRINS AS SCAFFOLDS AND TEMPLATES FOR MOLECULAR DIVERSITY, CATALYSIS, AND INCLUSION PHENOMENA [J].

HANESSIAN, S ;

BENALIL, A ;

LAFERRIERE, C .

JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (15) :4786-4797

← 1 2 3 →