Nuclear Medicine Imaging of the Pediatric Musculoskeletal System

被引:11
作者
Shammas, Amer [1 ,2 ]
机构
[1] Univ Toronto, Div Nucl Med, Hosp Sick Children, Dept Diagnost Imaging, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Dept Med Imaging, Toronto, ON M5G 1X8, Canada
关键词
Children; musculoskeletal; bone; scintigraphy; PET/CT; FDG; LANGERHANS CELL HISTIOCYTOSIS; CALVE-PERTHES-DISEASE; BROWN ADIPOSE-TISSUE; PRIMARY BONE-TUMORS; FDG-PET; F-18-FDG PET/CT; TOMOGRAPHY/COMPUTED TOMOGRAPHY; CONVENTIONAL RADIOGRAPHY; SCINTIGRAPHIC FINDINGS; SKELETAL SCINTIGRAPHY;
D O I
10.1055/s-0029-1237687
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Bone scintigraphy is a common pediatric nuclear medicine procedure and plays a significant role in the diagnosis of skeletal infection, trauma, and benign and malignant bone tumors. There is a complementary role for bone scintigraphy in the assessment of a child with suspected nonaccidental injury. High-quality images require careful attention to technique and positioning in children. Additional techniques such as magnification and single-photon emission computed tomography (SPECT) can be used for special indications and localization. Combined functional and anatomic imaging using SPECT/computed tomography (CT) imaging systems can improve diagnostic accuracy. Positron emission tomography (PET) using fluorine-18 fluorodeoxyglucose (FDG) is being applied with increasing frequency in the evaluation of children with malignancy. To interpret F-18-FDG PET appropriately, it is essential to know the normal physiological distribution. Using combined F-18-FDG PET/CT improves specificity and localization. This article reviews the common indications for bone scintigraphy and F-18-FDG PET/CT in benign and malignant pediatric musculoskeletal disease.
引用
收藏
页码:159 / 180
页数:22
相关论文
共 82 条
[1]  
Anderson MW, 1996, RADIOLOGY, V199, P1
[2]   FDG PET of primary benign and malignant bone tumors: Standardized uptake value in 52 lesions [J].
Aoki, J ;
Watanabe, H ;
Shinozaki, T ;
Takagishi, K ;
Ishijima, H ;
Oya, N ;
Sato, N ;
Inoue, T ;
Endo, K .
RADIOLOGY, 2001, 219 (03) :774-777
[3]   Positron emission tomography/computed tomography with 18fluoro-deoxyglucose in the detection of local recurrence and distant metastases of pediatric sarcoma [J].
Arush, M. Weyl Ben ;
Israel, O. ;
Postovsky, S. ;
Militianu, D. ;
Meller, I. ;
Zaidman, I. ;
Sapir, A. Even ;
Bar-Shalom, R. .
PEDIATRIC BLOOD & CANCER, 2007, 49 (07) :901-905
[4]   Langerhans' cell histiocytosis: pathology, imaging and treatment of skeletal involvement [J].
Azouz, EM ;
Saigal, G ;
Rodriguez, MM ;
Podda, A .
PEDIATRIC RADIOLOGY, 2005, 35 (02) :103-115
[5]   Guidelines for the use of PET-CT in children [J].
Barrington, Sally F. ;
Begent, Joanna ;
Lyunch, Thomas ;
Schleyer, Paul ;
Biassoni, Lorenzo ;
Ramsden, William ;
Kane, Thomas ;
Stoneham, Sara ;
Brooks, Margaret ;
Hain, Sharon F. .
NUCLEAR MEDICINE COMMUNICATIONS, 2008, 29 (05) :418-424
[6]  
Barrington SF, 1996, J NUCL MED, V37, P1127
[7]  
Bernard EJ, 1998, J NUCL MED, V39, P1983
[8]   Conversion of FDG PET Activity of Fibrous Dysplasia of the Skull Late in Life Mimicking Metastatic Disease [J].
Bonekamp, David ;
Jacene, Heather ;
Bartelf, Detlef ;
Aygun, Nafi .
CLINICAL NUCLEAR MEDICINE, 2008, 33 (12) :909-911
[9]  
Brenner W, 2003, J NUCL MED, V44, P930
[10]  
Brix G, 2005, J NUCL MED, V46, P608